PSTPIP1 and NAV2

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		PSTPIP1	NAV2
Description		proline-serine-threonine phosphatase interacting protein 1	neuron navigator 2
Image
GO Annotations	Cellular Component	Uropod Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Lamellipodium Cleavage Furrow Perinuclear Region Of Cytoplasm	Interstitial Matrix Nucleoplasm
	Molecular Function	Protein Binding Cytoskeletal Protein Binding Identical Protein Binding	DNA Helicase Activity Protein Binding ATP Binding Heparin Binding
	Biological Process	Endocytosis Inflammatory Response Cell Adhesion Signal Transduction Innate Immune Response	Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Nervous System Development Sensory Perception Of Sound Sensory Perception Of Smell Locomotory Behavior Optic Nerve Development Glossopharyngeal Nerve Development Vagus Nerve Development Neurogenesis DNA Duplex Unwinding
Pathways		The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection
Drugs
Diseases		Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome
GWAS		Neurofibrillary tangles ( 31497858)	Adverse response to drug ( 30420678) Atrial fibrillation ( 30061737 29892015) Bone mineral density x blood lead interaction in current smokers (2df test) ( 29518117) Coronary artery aneurysm in Kawasaki disease ( 27171184) General cognitive ability ( 29844566) Hepatitis ( 25705159) Low susceptibility to hepatitis C infection ( 31206233) Macular thickness ( 30535121) Monobrow ( 27182965) Obesity-related traits ( 23251661) PR interval ( 30046033) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762) Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) ( 30166627) Smoking initiation (ever regular vs never regular) ( 30679032) Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306) Waist circumference ( 28552196)
Interacting Genes		42 interacting genes: ABL1 AXIN1 BUB3 CCDC172 CD2 CD2AP CHD4 DNM2 EXOC5 FAM90A1 FASLG FBXL18 HMG20A KHDRBS1 LSM4 MEFV MFGE8 MVP NAV2 PCDHB14 PRPF31 PTPN12 PTPN18 RINT1 RTP5 RXRB SDCBP SH2D4A SHBG SPG7 SYCE1 TFIP11 TRAF3IP3 TTC1 TULP3 UBE2W WAS WASF1 WASF2 WASL ZNF175 ZNF688	12 interacting genes: ADAT2 APC CFAP58 ING4 ING5 MORF4L1 PIAS2 PRPF3 PSTPIP1 RBM15 RBM15B RRAS
Entrez ID		9051	89797
HPRD ID		05891	07385
Ensembl ID		ENSG00000140368	ENSG00000166833
Uniprot IDs		A0A0S2Z5P3 O43586	A7E2D6 Q8IVL1
PDB IDs		2DIL	2YRN
Enriched GO Terms of Interacting Partners?
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