SPAG9 and MAX

Number of citations of the paper that reports this interaction (PubMedID 12391307)
34

Data Source:
HPRD (in vivo, in vitro)

		SPAG9	MAX
Description		sperm associated antigen 9	MYC associated factor X
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GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Lysosomal Membrane Cytosol Centriolar Satellite Perinuclear Region Of Cytoplasm Extracellular Exosome	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm PML Body Dendrite Protein-DNA Complex MLL1 Complex RNA Polymerase II Transcription Factor Complex
	Molecular Function	MAP-kinase Scaffold Activity Protein Binding JUN Kinase Binding Kinesin Binding Receptor Signaling Complex Scaffold Activity Identical Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Identical Protein Binding Protein-containing Complex Binding Protein Dimerization Activity E-box Binding
	Biological Process	Activation Of JUN Kinase Activity Vesicle-mediated Transport Positive Regulation Of Cell Migration Lysosome Localization Retrograde Transport, Endosome To Golgi Positive Regulation Of Neuron Differentiation Striated Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation	G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Cellular Response To Starvation Response To Insulin Positive Regulation Of Transcription By RNA Polymerase II Response To Axon Injury Neuron Apoptotic Process Retina Development In Camera-type Eye Protein-containing Complex Assembly Negative Regulation Of G0 To G1 Transition Cellular Response To Peptide Hormone Stimulus
Pathways		Myogenesis Myogenesis	Transcription of E2F targets under negative control by DREAM complex Cyclin E associated events during G1/S transition Cyclin A:Cdk2-associated events at S phase entry Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Body fat mass ( 28552196) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483)	Anthropometric traits ( 19260139) Blood protein levels ( 30072576) Blood trace element (Zn levels) ( 23720494) Height ( 31562340) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular hemoglobin concentration ( 29403010 27863252) Mean corpuscular volume ( 27863252) Mean platelet volume ( 27863252) Obesity-related traits ( 23251661) Platelet count ( 27863252) Red blood cell count ( 27863252) Red blood cell traits ( 23222517)
Interacting Genes		12 interacting genes: ARF6 KLC1 MAP1LC3B MAP2K4 MAP3K3 MAPK14 MAPK8 MAX MYC NFKB1 PNRC2 TP53BP1	42 interacting genes: BANP CASP5 CASP7 CLIP2 COPS5 CSNK2A1 CUX1 EP300 EPAS1 FTH1 FUS GABBR1 HIF1A MAD1L1 MAPK14 MGA MNT MSH2 MXD1 MXD3 MXD4 MXI1 MYC MYCL MYCLP1 MYCN PLEKHA5 PLEKHF2 PLIN3 RPL34 RPL35 SMAD3 SMAD4 SNIP1 SPAG9 TAF1 TEAD1 TRRAP TUBA1A TXLNG UNC45A ZBTB17
Entrez ID		9043	4149
HPRD ID		10398	01113
Ensembl ID		ENSG00000008294	ENSG00000125952
Uniprot IDs		O60271 Q5JB53	A0A024R682 G3V302 P61244 Q8TAX8
PDB IDs		2W83	1AN2 1HLO 1NKP 1NLW 1R05 5EYO 6G6J 6G6K 6G6L
Enriched GO Terms of Interacting Partners?
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