MAX and FUS

Number of citations of the paper that reports this interaction (PubMedID 20195357)
30

Data Source:
BioGRID (pull down)

		MAX	FUS
Description		MYC associated factor X	FUS RNA binding protein
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm PML Body Dendrite Protein-DNA Complex MLL1 Complex RNA Polymerase II Transcription Factor Complex	Nucleus Nucleoplasm Polysome Perikaryon Dendritic Spine Head Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Identical Protein Binding Protein-containing Complex Binding Protein Dimerization Activity E-box Binding	DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity RNA Binding MRNA 3'-UTR Binding Protein Binding Estrogen Receptor Binding Myosin V Binding Ionotropic Glutamate Receptor Binding Identical Protein Binding Metal Ion Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Cellular Response To Starvation Response To Insulin Positive Regulation Of Transcription By RNA Polymerase II Response To Axon Injury Neuron Apoptotic Process Retina Development In Camera-type Eye Protein-containing Complex Assembly Negative Regulation Of G0 To G1 Transition Cellular Response To Peptide Hormone Stimulus	MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II RNA Splicing Regulation Of RNA Splicing MRNA Stabilization Protein Homooligomerization Cellular Response To Calcium Ion Positive Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways		Transcription of E2F targets under negative control by DREAM complex Cyclin E associated events during G1/S transition Cyclin A:Cdk2-associated events at S phase entry Transcriptional Regulation by E2F6	mRNA Splicing - Major Pathway
Drugs
Diseases			Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease Myxoid liposarcoma
GWAS		Anthropometric traits ( 19260139) Blood protein levels ( 30072576) Blood trace element (Zn levels) ( 23720494) Height ( 31562340) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular hemoglobin concentration ( 29403010 27863252) Mean corpuscular volume ( 27863252) Mean platelet volume ( 27863252) Obesity-related traits ( 23251661) Platelet count ( 27863252) Red blood cell count ( 27863252) Red blood cell traits ( 23222517)	Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756)
Interacting Genes		42 interacting genes: BANP CASP5 CASP7 CLIP2 COPS5 CSNK2A1 CUX1 EP300 EPAS1 FTH1 FUS GABBR1 HIF1A MAD1L1 MAPK14 MGA MNT MSH2 MXD1 MXD3 MXD4 MXI1 MYC MYCL MYCLP1 MYCN PLEKHA5 PLEKHF2 PLIN3 RPL34 RPL35 SMAD3 SMAD4 SNIP1 SPAG9 TAF1 TEAD1 TRRAP TUBA1A TXLNG UNC45A ZBTB17	45 interacting genes: AKT1 ARID1A ATXN1L CTNNB1 ESRRA EWSR1 GRIN1 GRIN2D IL7R ILF3 KHDRBS3 MAX MDH1 NKD2 NUPR1 POLR2A PRMT1 PSMB7 PTBP1 RBMX RELA RXRA SAFB2 SF1 SFPQ SMARCB1 SMARCC1 SMARCC2 SMARCD1 SPI1 SRRM1 SRSF10 SRSF2 SRSF4 SRSF9 SS18 SUV39H1 TARDBP TDRD3 THRA TNIP1 UBQLN2 WBP4 YBX1 ZMYM2
Entrez ID		4149	2521
HPRD ID		01113	00660
Ensembl ID		ENSG00000125952	ENSG00000089280
Uniprot IDs		A0A024R682 G3V302 P61244 Q8TAX8	P35637 Q13344 Q6IBQ5
PDB IDs		1AN2 1HLO 1NKP 1NLW 1R05 5EYO 6G6J 6G6K 6G6L	2LA6 2LCW 4FDD 4FQ3 5W3N 5XRR 5XSG 5YVG 5YVH 5YVI 6BWZ 6BXV 6BZP 6G99 6GBM 6KJ1 6KJ2 6KJ3 6KJ4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?