SPAG9 and KLC1

Number of citations of the paper that reports this interaction (PubMedID 15987681)
24

Data Source:
HPRD (in vivo, two hybrid)

		SPAG9	KLC1
Description		sperm associated antigen 9	kinesin light chain 1
Image
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Lysosomal Membrane Cytosol Centriolar Satellite Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytosol Kinesin Complex Microtubule Membrane Growth Cone Cytoplasmic Vesicle
	Molecular Function	MAP-kinase Scaffold Activity Protein Binding JUN Kinase Binding Kinesin Binding Receptor Signaling Complex Scaffold Activity Identical Protein Binding	Motor Activity Microtubule Motor Activity Protein Binding
	Biological Process	Activation Of JUN Kinase Activity Vesicle-mediated Transport Positive Regulation Of Cell Migration Lysosome Localization Retrograde Transport, Endosome To Golgi Positive Regulation Of Neuron Differentiation Striated Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation	Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Stress Granule Disassembly
Pathways		Myogenesis Myogenesis	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Body fat mass ( 28552196) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 28892062 25673413) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 25056061) Smoking behaviour (cigarette pack-years) ( 30679032) Urate levels ( 31578528)
Interacting Genes		12 interacting genes: ARF6 KLC1 MAP1LC3B MAP2K4 MAP3K3 MAPK14 MAPK8 MAX MYC NFKB1 PNRC2 TP53BP1	21 interacting genes: APP BNIP2 CCDC114 CLSTN1 HSPB1 KIF2A KIF5C KLC2 KRT31 LRSAM1 MAPK6 MAPK8IP1 MAPK8IP2 MAPK8IP3 NIN ODF1 PCM1 PLEKHM2 SNCA SPAG9 YWHAB
Entrez ID		9043	3831
HPRD ID		10398	02489
Ensembl ID		ENSG00000008294	ENSG00000126214
Uniprot IDs		O60271 Q5JB53	Q07866 Q7RTQ2
PDB IDs		2W83	3NF1 5OJ8
Enriched GO Terms of Interacting Partners?
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