UBE2M and UBA3

Number of citations of the paper that reports this interaction (PubMedID 15694336)
74

Data Source:
HPRD (in vitro)

		UBE2M	UBA3
Description		ubiquitin conjugating enzyme E2 M	ubiquitin like modifier activating enzyme 3
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GO Annotations	Cellular Component	Nucleoplasm Cytosol	Nucleus Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding NEDD8 Transferase Activity Ubiquitin Conjugating Enzyme Activity	Protein Binding ATP Binding Nuclear Receptor Binding NEDD8 Activating Enzyme Activity NEDD8 Transferase Activity Identical Protein Binding Protein-containing Complex Binding Protein Heterodimerization Activity
	Biological Process	Cellular Protein Modification Process Protein Ubiquitination Positive Regulation Of Neuron Apoptotic Process Post-translational Protein Modification Protein Neddylation	Cellular Protein Modification Process Proteolysis Endomitotic Cell Cycle Protein Modification By Small Protein Conjugation Post-translational Protein Modification Protein Neddylation Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle
Pathways		TGF-beta receptor signaling activates SMADs Dectin-1 mediated noncanonical NF-kB signaling NIK - noncanonical NF-kB signaling Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Dectin-1 mediated noncanonical NF-kB signaling NIK - noncanonical NF-kB signaling Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes		28 interacting genes: APP CAND1 CBL CPNE1 CPNE2 CPNE4 CUL1 CUL7 DCUN1D1 DCUN1D2 DCUN1D3 DCUN1D4 DCUN1D5 FBXO7 ITCH MARCHF7 NEDD4 NEDD8 PINK1 PRKN RBX1 RNF111 RNF7 SENP8 SMURF1 TERF1 TP53 UBA3	9 interacting genes: CHD3 CPNE2 IMPA2 KDM1A NAE1 NEDD8 UBE2D2 UBE2F UBE2M
Entrez ID		9040	9039
HPRD ID		04414	04413
Ensembl ID		ENSG00000130725	ENSG00000144744
Uniprot IDs		A0A024R4T4 P61081	Q8TBC4
PDB IDs		1TT5 1Y8X 2NVU 3TDU 3TDZ 4GAO 4P5O	1R4M 1R4N 1TT5 1Y8X 1YOV 2LQ7 2NVU 3DBH 3DBL 3DBR 3FN1 3GZN 5JJM
Enriched GO Terms of Interacting Partners?
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