APLN and GET3

Number of citations of the paper that reports this interaction (PubMedID 22505607)
27

Data Source:
BioGRID (pull down)

		APLN	GET3
Description		apelin	guided entry of tail-anchored proteins factor 3, ATPase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Perinuclear Region Of Cytoplasm	Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Membrane GET Complex Extracellular Exosome
	Molecular Function	Signaling Receptor Binding Hormone Activity Apelin Receptor Binding Identical Protein Binding	Protein Binding ATP Binding Arsenite Transmembrane Transporter Activity ATPase Activity Metal Ion Binding
	Biological Process	Angiogenesis Regulation Of The Force Of Heart Contraction Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Gastrulation Lactation Negative Regulation Of Gene Expression Viral Process Positive Regulation Of Heat Generation Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Phosphorylation Drinking Behavior Regulation Of Respiratory Gaseous Exchange Negative Regulation Of Blood Pressure Positive Regulation Of Heart Contraction Negative Regulation Of Vasoconstriction Positive Regulation Of Corticotropin Secretion Positive Regulation Of Corticotropin-releasing Hormone Secretion Apelin Receptor Signaling Pathway Coronary Vasculature Development Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II Positive Regulation Of G Protein-coupled Receptor Internalization Negative Regulation Of Vascular Smooth Muscle Cell Proliferation Positive Regulation Of Vascular Endothelial Cell Proliferation	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Arsenite Transport IRE1-mediated Unfolded Protein Response Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs			ATP
Diseases
GWAS
Interacting Genes		6 interacting genes: APLNR GET3 MDFI PLSCR4 PSMA3 RBPMS	14 interacting genes: APLN ASPH CACNA1A GET4 GPX7 HILPDA PFDN1 SEC61A1 SEC61B STATH STX5 TK1 TTR VAMP2
Entrez ID		8862	439
HPRD ID		02246	03555
Ensembl ID		ENSG00000171388	ENSG00000198356
Uniprot IDs		Q9ULZ1	O43681
PDB IDs
Enriched GO Terms of Interacting Partners?
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