KRT38 and KRT5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KRT38	KRT5
Description		keratin 38	keratin 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Extracellular Exosome	Nucleus Cytoplasm Cytosol Intermediate Filament Plasma Membrane Membrane Keratin Filament Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding
	Biological Process	Keratinization Cornification	Cytoskeleton Organization Epidermis Development Keratinization Hemidesmosome Assembly Cornification
Pathways		Keratinization Formation of the cornified envelope	Type I hemidesmosome assembly Keratinization Formation of the cornified envelope
Drugs			Zinc
Diseases			Dowling-Degos disease Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
GWAS			Basal cell carcinoma ( 31174203 24403052 25855136 27539887) Keratinocyte cancer (MTAG) ( 31174203) Non-melanoma skin cancer ( 29739929) Squamous cell carcinoma ( 31174203)
Interacting Genes		46 interacting genes: AMOTL2 ANKRD36BP1 BEX2 C19orf57 C1orf216 CCDC146 CD300A CEP57L1 FAM90A1 GLRX3 GNG10 HAUS1 HDAC4 HGS HMG20B HOXA1 KDM1A KLHL38 KRT2 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT79 KRT8 KRT81 KRT83 LHX4 MAGEB4 PIK3R2 PIN1 PSMA1 PSMC5 PTGER3 RHPN1-AS1 SCNM1 TXLNA TXLNB TXNDC5 USHBP1 ZFYVE21 ZNF20 ZNF417 ZNF587	17 interacting genes: ALOX12 ALOX12B APC DSP DST EVPL KIFC3 KRT1 KRT14 KRT15 KRT18 KRT31 KRT38 KRT40 PKP2 TCHP UBE3A
Entrez ID		8687	3852
HPRD ID		05176	01010
Ensembl ID		ENSG00000171360	ENSG00000186081
Uniprot IDs		O76015	P13647
PDB IDs			3TNU
Enriched GO Terms of Interacting Partners?
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