Wiki-CORONA
  • About
  • Search
  • Browse
  • Data Sources
  • People
  • Funding
  • Advanced Search

KRT5

Description keratin 5
Image
GO Annotations Cellular Component
  • Nucleus
  • Cytoplasm
  • Cytosol
  • Intermediate Filament
  • Plasma Membrane
  • Membrane
  • Keratin Filament
  • Extracellular Exosome
Molecular Function
  • Structural Constituent Of Cytoskeleton
  • Protein Binding
  • Scaffold Protein Binding
Biological Process
  • Cytoskeleton Organization
  • Epidermis Development
  • Keratinization
  • Hemidesmosome Assembly
  • Cornification
Pathways
  • Type I hemidesmosome assembly
  • Keratinization
  • Formation of the cornified envelope
Drugs
  • Zinc
Diseases
  • Dowling-Degos disease
  • Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
GWAS
  • Basal cell carcinoma ( 31174203 24403052 25855136 27539887)
  • Keratinocyte cancer (MTAG) ( 31174203)
  • Non-melanoma skin cancer ( 29739929)
  • Squamous cell carcinoma ( 31174203)
Interacting Genes 17 interacting genes: ALOX12 ALOX12B APC DSP DST EVPL KIFC3 KRT1 KRT14 KRT15 KRT18 KRT31 KRT38 KRT40 PKP2 TCHP UBE3A
Entrez ID 3852
HPRD ID 01010
Ensembl ID ENSG00000186081
Uniprot IDs P13647
PDB IDs 3TNU
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

  • Tweet