EIF3F and FBXO32

Number of citations of the paper that reports this interaction (PubMedID 18354498)
89

Data Source:
BioGRID (pull down)

		EIF3F	FBXO32
Description		eukaryotic translation initiation factor 3 subunit F	F-box protein 32
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3m	Nucleoplasm Cytoplasm Cytosol SCF Ubiquitin Ligase Complex Z Disc
	Molecular Function	Translation Initiation Factor Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Translation Initiation Factor Binding	Protein Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Protein Deubiquitination IRES-dependent Viral Translational Initiation	Protein Polyubiquitination Response To Denervation Involved In Regulation Of Muscle Adaptation Protein Ubiquitination Post-translational Protein Modification Cellular Response To Dexamethasone Stimulus
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	Neddylation FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Quercetin
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Depression (quantitative trait) ( 20800221)	Atrial fibrillation ( 30061737 29892015) Glaucoma ( 30054594) Glaucoma (primary open-angle) ( 29891935) Intraocular pressure ( 29617998 29785010 31959993 30054594) Psychosis proneness (hypomanic personality scale and perceptual aberration scale) ( 28525603) Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale) ( 28525603) Psychosis proneness (hypomanic personality scale and revised social anhedonia scale) ( 28525603) Psychosis proneness (hypomanic personality scale) ( 28525603)
Interacting Genes		19 interacting genes: APP ATXN1 CDK11A CDK11B CDK19 DKC1 EEF1A1 EIF3M FBXO32 HAX1 HNRNPK HTR2A MCPH1 MSH4 MTOR PTN RPS6KB1 SHBG SMAD9	8 interacting genes: CDC34 EIF3F MLH1 MYOD1 SH3GL1 SH3GL2 SH3GL3 SKP1
Entrez ID		8665	114907
HPRD ID		04887	05966
Ensembl ID		ENSG00000175390	ENSG00000156804
Uniprot IDs		O00303	A0A024R9F3 I6L984 Q0VAQ6 Q498Y9 Q969P5
PDB IDs		3J8B 3J8C
Enriched GO Terms of Interacting Partners?
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