EIF3F

Description		eukaryotic translation initiation factor 3 subunit F
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GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
	Molecular Function	Translation Initiation Factor Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Translation Initiation Factor Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Protein Deubiquitination IRES-dependent Viral Translational Initiation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs		Quercetin
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Depression (quantitative trait) ( 20800221)
Interacting Genes		19 interacting genes: APP ATXN1 CDK11A CDK11B CDK19 DKC1 EEF1A1 EIF3M FBXO32 HAX1 HNRNPK HTR2A MCPH1 MSH4 MTOR PTN RPS6KB1 SHBG SMAD9
Entrez ID		8665
HPRD ID		04887
Ensembl ID		ENSG00000175390
Uniprot IDs		O00303
PDB IDs		3J8B 3J8C
Enriched GO Terms of Interacting Partners?
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