BLZF1 and LMO2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		BLZF1	LMO2
Description		basic leucine zipper nuclear factor 1	LIM domain only 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus	Nucleoplasm Transcription Factor Complex
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding BHLH Transcription Factor Binding Metal Ion Binding Cofactor Binding E-box Binding
	Biological Process	Regulation Of Cell Growth Regulation Of Transcription, DNA-templated Golgi Organization Golgi To Plasma Membrane Protein Transport	Multicellular Organism Development MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Thyroid Hormone Stimulus Regulation Of Hematopoietic Stem Cell Differentiation
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization	RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs
Diseases			Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS			Cognitive performance ( 19734545) Iron status biomarkers (transferrin saturation) ( 28334935) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red blood cell count ( 27863252)
Interacting Genes		52 interacting genes: AKAP9 AMOTL2 BANP BCL6 BEX2 CARD9 CCDC33 CHCHD3 CINP CKS2 DNMT3L EWSR1 FBF1 FHL2 FRMD6 GEM GORASP2 HCLS1 HOXA1 IQUB KDM1A KLHL38 LMO1 LMO2 OAZ3 PRKAB2 PRMT6 PSMA1 PTPN11 RAB2A RAB2B RAB39A RANBP3 RHOJ SCNM1 SELENOS SMAD3 SMARCB1 SRA1 SSX2 SUV39H2 TBC1D7 TRAPPC2L TSC22D4 TXNDC5 VPS28 ZBTB24 ZGPAT ZMAT1 ZNF410 ZNF688 ZZZ3	97 interacting genes: ABI2 ADAMTSL4 AFDN AGTRAP AIMP2 ALDH6A1 AXIN1 BANP BEX2 BLZF1 C1orf94 CALCOCO2 CBY2 CCDC33 CDC25A CDC5L CDX4 CLHC1 CMTM5 CORO1A CORO1C DAZAP2 DBF4B DDIT3 DRAP1 EHMT2 ELF2 ERBIN FHL3 GATA1 GATA2 GATA3 GFAP GOLGA2 GRB2 HNRNPC HNRNPM HOOK1 IFT43 IHO1 IKZF3 ISL1 KANK2 KDM5A KIF3B KRT15 KRT40 KRTAP10-7 LDB1 LYL1 LZTS2 MAGEA8 MAPRE1 MAPRE2 MAPRE3 MBIP MRFAP1L1 MTUS2 N4BP2L2 NCAPH2 NHLH1 NIF3L1 NOTCH2NLA NUP62 NUTM1 PDE9A PHC2 PRKG1 RBBP8 REL RELA RINT1 RLIM ROCK1 SAXO1 SKP1 SMAD2 SOX5 SP1 SSX2IP STAT1 STAT3 STIP1 TAL1 TAL2 TFPT TLE5 TLX3 TRIM23 TRIM54 TRIP6 TSC22D4 TUFT1 UBA6 UBE2I ZFP64 ZNF24
Entrez ID		8548	4005
HPRD ID		16367	01586
Ensembl ID		ENSG00000117475	ENSG00000135363
Uniprot IDs		Q9H2G9	P25791
PDB IDs			2XJY 2XJZ 2YPA 4KFZ
Enriched GO Terms of Interacting Partners?
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