BLZF1 and FHL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		BLZF1	FHL2
Description		basic leucine zipper nuclear factor 1	four and a half LIM domains 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus	Nucleus Nucleoplasm Focal Adhesion Z Disc M Band
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Identical Protein Binding Metal Ion Binding Androgen Receptor Binding
	Biological Process	Regulation Of Cell Growth Regulation Of Transcription, DNA-templated Golgi Organization Golgi To Plasma Membrane Protein Transport	Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation Response To Hormone Regulation Of Lipid Metabolic Process Androgen Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Atrial Cardiac Muscle Cell Development Ventricular Cardiac Muscle Cell Development Heart Trabecula Formation Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization	PPARA activates gene expression
Drugs
Diseases
GWAS			Body fat mass ( 28552196) Household income (MTAG) ( 31844048) Lung cancer in ever smokers ( 28604730) Pulse pressure ( 30224653 30578418)
Interacting Genes		52 interacting genes: AKAP9 AMOTL2 BANP BCL6 BEX2 CARD9 CCDC33 CHCHD3 CINP CKS2 DNMT3L EWSR1 FBF1 FHL2 FRMD6 GEM GORASP2 HCLS1 HOXA1 IQUB KDM1A KLHL38 LMO1 LMO2 OAZ3 PRKAB2 PRMT6 PSMA1 PTPN11 RAB2A RAB2B RAB39A RANBP3 RHOJ SCNM1 SELENOS SMAD3 SMARCB1 SRA1 SSX2 SUV39H2 TBC1D7 TRAPPC2L TSC22D4 TXNDC5 VPS28 ZBTB24 ZGPAT ZMAT1 ZNF410 ZNF688 ZZZ3	98 interacting genes: ADAM17 AK1 APP AR ARHGAP9 ATXN1 BANP BIN1 BLZF1 BMPR2 BRCA1 CAPN1 CARD8 CCDC92 CKM CREBBP CSK CSN2 CTNNB1 DCP1A DPF2 DTX2 DUSP10 E2F1 E2F2 E2F3 E2F4 EP300 ESR1 FHL1 FHL3 FHL5 FOXO1 GLYR1 GNG12 HAND1 HCK HSPB2 ID3 IDH1 IER3 IGFBP5 IKZF4 INCA1 ITGA3 ITGA7 ITGB1 ITGB2 ITGB5 ITGB6 JUP KANK2 KIAA1217 MCM7 MDM2 MYBPC1 NIBAN1 NRF1 PFKM PHB2 PSEN2 PUF60 RAI2 REL REV1 RFX3 RUNX2 SAP30BP SAXO1 SFPQ SIGLEC6 SLC34A1 SMAD2 SMAD3 SMAD4 SP2 SRF STAT3 SUMO1P1 TNFRSF11A TRAF6 TRIM55 TRIM63 TTN WT1 ZBTB16 ZBTB25 ZFP64 ZFYVE9 ZMYM4 ZNF131 ZNF212 ZNF3 ZNF331 ZNF408 ZNF417 ZNF626 ZNF638
Entrez ID		8548	2274
HPRD ID		16367	04026
Ensembl ID		ENSG00000117475	ENSG00000115641
Uniprot IDs		Q9H2G9	Q14192 Q2XQU9 Q6I9R8
PDB IDs			1X4K 1X4L 2D8Z 2MIU
Enriched GO Terms of Interacting Partners?
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