SHANK3 and USP8

  • Number of citations of the paper that reports this interaction (PubMedID 29735556)
  • 4
  • Data Source:
  • BioGRID (enzymatic study)

SHANK3

USP8

Description SH3 and multiple ankyrin repeat domains 3 ubiquitin specific peptidase 8
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Extremely high intelligence ( 29520040)
  • Fibrinogen ( 23969696)
  • Fibrinogen levels ( 28107422 26561523)
  • Intelligence (MTAG) ( 29326435)
  • Memory dysfunction in frontotemporal lobe dementia ( 29724592)
Interacting Genes 17 interacting genes: ABCC2 CNKSR2 COPS5 CRKL CSNK2B DLGAP1 DLGAP2 DLGAP3 DLGAP4 GRB2 MAPK1 NCK1 PAX6 PPP1CC RPS6KA1 SPTAN1 USP8 40 interacting genes: BACE1 BIRC6 CFLAR CHMP1A CHMP1B CHMP2A CHMP2B CHMP4C CHMP7 DNAJB6 EPS15 GRAP2 GRB2 H2AC20 H2BC21 KIF23 NBR1 PJA1 PLA2G2A RASGRF1 RNF41 SEC31A SHANK1 SHANK3 SLBP SNCA SPP1 SRC STAM STAM2 TRIM54 TRIM55 TRIM63 UBC USP15 USP21 USP28 YWHAG YWHAQ YWHAZ
Entrez ID 85358 9101
HPRD ID 18979 04405
Ensembl ID ENSG00000251322 ENSG00000138592
Uniprot IDs A0A024R5S4 A8K8N5 P40818
PDB IDs 1WHB 2A9U 2GFO 2GWF 3N3K 6F09
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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