NUDT16L1 and LRRK1

Number of citations of the paper that reports this interaction (PubMedID 29513927)
4

Data Source:
BioGRID (pull down)

		NUDT16L1	LRRK1
Description		nudix hydrolase 16 like 1	leucine rich repeat kinase 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Mitochondrion Cytosol
	Molecular Function	RNA Binding Protein Binding SnoRNA Binding Protein Homodimerization Activity M7G(5')pppN Diphosphatase Activity Nucleotide Phosphatase Activity, Acting On Free Nucleotides Phosphodiesterase Decapping Endonuclease Activity	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding Metal Ion Binding
	Biological Process	MRNA Catabolic Process SnoRNA Catabolic Process Dephosphorylation RNA Phosphodiester Bond Hydrolysis, Endonucleolytic Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining	Protein Phosphorylation Osteoclast Development Bone Resorption Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS			Central corneal thickness ( 28171582 31798171 29760442) Corneal structure ( 23291589) Height ( 28552196)
Interacting Genes		7 interacting genes: APP FBXO7 LRRK1 NEDD4L PNMA1 TP53BP1 TRAF2	53 interacting genes: ABL1 BAG1 BAG2 BAG3 BAG5 BLOC1S5 C11orf52 CBLB CCL21 CD2BP2 CDC42EP3 CHGB CKAP2 CLVS1 CPLX3 CWC15 ECHS1 EGFR ENKUR EPHA8 FAM184A FBXL14 FGFR2 FLT4 FOXP1 GAK GNAZ GPBP1L1 ITCH KIF20A MATK MTG1 NEK1 NUDT16L1 ODF2 PAK6 PDCD4 PLK1 POLR2M RAB29 RET SCEL SELENOS SH2D2A SNX21 SNX9 STUB1 TCF25 TEC TEX33 TIRAP TM2D3 VGLL4
Entrez ID		84309	79705
HPRD ID		15309	14319
Ensembl ID		ENSG00000168101	ENSG00000154237
Uniprot IDs		B2RD96 Q9BRJ7 W4VSQ8	Q38SD2
PDB IDs		3KVH 5ZCJ 6CO1 6D0L
Enriched GO Terms of Interacting Partners?
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