LRRK1 and CPLX3

Number of citations of the paper that reports this interaction (PubMedID 29513927)
4

Data Source:
BioGRID (pull down)

		LRRK1	CPLX3
Description		leucine rich repeat kinase 1	complexin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol	Cytosol Cell Junction SNARE Complex Terminal Bouton Photoreceptor Ribbon Synapse Anchored Component Of Synaptic Vesicle Membrane Anchored Component Of Presynaptic Active Zone Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding Metal Ion Binding	SNARE Binding Neurotransmitter Transporter Activity Syntaxin Binding
	Biological Process	Protein Phosphorylation Osteoclast Development Bone Resorption Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Intracellular Signal Transduction	Visual Perception Synaptic Vesicle Exocytosis Insulin Secretion Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Regulation Of Neurotransmitter Secretion Response To Stimulus
Pathways
Drugs
Diseases
GWAS		Central corneal thickness ( 28171582 31798171 29760442) Corneal structure ( 23291589) Height ( 28552196)	Caffeine consumption ( 21490707) Coffee consumption ( 21876539) Diastolic blood pressure ( 19430483 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		53 interacting genes: ABL1 BAG1 BAG2 BAG3 BAG5 BLOC1S5 C11orf52 CBLB CCL21 CD2BP2 CDC42EP3 CHGB CKAP2 CLVS1 CPLX3 CWC15 ECHS1 EGFR ENKUR EPHA8 FAM184A FBXL14 FGFR2 FLT4 FOXP1 GAK GNAZ GPBP1L1 ITCH KIF20A MATK MTG1 NEK1 NUDT16L1 ODF2 PAK6 PDCD4 PLK1 POLR2M RAB29 RET SCEL SELENOS SH2D2A SNX21 SNX9 STUB1 TCF25 TEC TEX33 TIRAP TM2D3 VGLL4	1 interacting genes: LRRK1
Entrez ID		79705	594855
HPRD ID		14319	18854
Ensembl ID		ENSG00000154237	ENSG00000213578
Uniprot IDs		Q38SD2	A0A384N6F4 Q8WVH0
PDB IDs
Enriched GO Terms of Interacting Partners?
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