PCGF6 and CBX6

Number of citations of the paper that reports this interaction (PubMedID 21282530)
40

Data Source:
BioGRID (pull down)

		PCGF6	CBX6
Description		polycomb group ring finger 6	chromobox 6
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Heterochromatin Nucleus Nucleoplasm PcG Protein Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	Single-stranded RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Histone H2A-K119 Monoubiquitination Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Inactivation Of X Chromosome By Genetic Imprinting Negative Regulation Of G0 To G1 Transition	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization
Pathways		Transcriptional Regulation by E2F6	Oxidative Stress Induced Senescence RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 25056061 29483656 23974872)	Bladder cancer ( 24163127 20972438)
Interacting Genes		22 interacting genes: BMI1 CBX6 CBX7 CDK7 E2F6 EIF2B2 H3-4 KDM5D MAGEA1 MAGEC2 MAGEE2 MAGEL2 PEX10 PNMA1 RAD18 RNF2 SS18L1 TRIM14 UBE2D3 UBE2U USP2 USP21	6 interacting genes: HOXC9 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6
Entrez ID		84108	23466
HPRD ID		07427	13005
Ensembl ID		ENSG00000156374	ENSG00000183741
Uniprot IDs		Q9BYE7	B0QXZ6 O95503
PDB IDs		2DJB	3GV6 3I90
Enriched GO Terms of Interacting Partners?
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