CBX6 and PCGF6

Number of citations of the paper that reports this interaction (PubMedID 21282530)
40

Data Source:
BioGRID (pull down)

		CBX6	PCGF6
Description		chromobox 6	polycomb group ring finger 6
Image
GO Annotations	Cellular Component	Heterochromatin Nucleus Nucleoplasm PcG Protein Complex	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	Single-stranded RNA Binding Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization	Negative Regulation Of Transcription By RNA Polymerase II Histone H2A-K119 Monoubiquitination Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Inactivation Of X Chromosome By Genetic Imprinting Negative Regulation Of G0 To G1 Transition
Pathways		Oxidative Stress Induced Senescence RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription	Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Bladder cancer ( 24163127 20972438)	Autism spectrum disorder or schizophrenia ( 28540026) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 25056061 29483656 23974872)
Interacting Genes		6 interacting genes: HOXC9 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6	22 interacting genes: BMI1 CBX6 CBX7 CDK7 E2F6 EIF2B2 H3-4 KDM5D MAGEA1 MAGEC2 MAGEE2 MAGEL2 PEX10 PNMA1 RAD18 RNF2 SS18L1 TRIM14 UBE2D3 UBE2U USP2 USP21
Entrez ID		23466	84108
HPRD ID		13005	07427
Ensembl ID		ENSG00000183741	ENSG00000156374
Uniprot IDs		B0QXZ6 O95503	Q9BYE7
PDB IDs		3GV6 3I90	2DJB
Enriched GO Terms of Interacting Partners?
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