PLEKHN1 and LPXN

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PLEKHN1	LPXN
Description		pleckstrin homology domain containing N1	leupaxin
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytoskeleton Plasma Membrane Mitochondrial Membrane	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Phosphatidylserine Binding Protein Binding Phosphatidic Acid Binding Cardiolipin Binding Phosphatidylinositol Phosphate Binding	Transcription Coregulator Activity Protein Binding Metal Ion Binding
	Biological Process	Response To Hypoxia Positive Regulation Of Apoptotic Process 3'-UTR-mediated MRNA Destabilization	Cell Adhesion Negative Regulation Of Cell Adhesion Signal Transduction Regulation Of Cell Adhesion Mediated By Integrin Negative Regulation Of B Cell Receptor Signaling Pathway Protein-containing Complex Assembly Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS		Height ( 31562340) Parkinson's disease ( 26227905)	Inflammatory bowel disease ( 23128233) Lymphoma ( 23349640) Pulse pressure ( 30578418) Ulcerative colitis ( 28067908)
Interacting Genes		11 interacting genes: CBY2 LPXN LZTS2 PUSL1 REL RFX6 TAX1BP1 TCF4 TP53BP2 TRAF1 TRIM27	27 interacting genes: GIT1 HDAC6 HOXA1 HOXC9 IKBKG IMP3 ITGA4 LIMS1 LMO1 MAP2K7 MAPK6 NDN NR3C1 PHF21A PLEKHH2 PLEKHN1 PLSCR4 POM121 PTK2 PTK2B PTPN12 RUNX1T1 SFI1 TXLNB VCL ZNF175 ZNF426
Entrez ID		84069	9404
HPRD ID		13190	05651
Ensembl ID		ENSG00000187583	ENSG00000110031
Uniprot IDs		Q494U1	B7Z5P7 O60711
PDB IDs			1X3H 4XEF 4XEK 4XEV
Enriched GO Terms of Interacting Partners?
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