LPXN and ZNF175

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		LPXN	ZNF175
Description		leupaxin	zinc finger protein 175
Image			No pdb structure
GO Annotations	Cellular Component	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm	Nucleoplasm Cytosol Intermediate Filament Cytoskeleton
	Molecular Function	Transcription Coregulator Activity Protein Binding Metal Ion Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Cell Adhesion Negative Regulation Of Cell Adhesion Signal Transduction Regulation Of Cell Adhesion Mediated By Integrin Negative Regulation Of B Cell Receptor Signaling Pathway Protein-containing Complex Assembly Regulation Of Nucleic Acid-templated Transcription	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Lymphoma ( 23349640) Pulse pressure ( 30578418) Ulcerative colitis ( 28067908)
Interacting Genes		27 interacting genes: GIT1 HDAC6 HOXA1 HOXC9 IKBKG IMP3 ITGA4 LIMS1 LMO1 MAP2K7 MAPK6 NDN NR3C1 PHF21A PLEKHH2 PLEKHN1 PLSCR4 POM121 PTK2 PTK2B PTPN12 RUNX1T1 SFI1 TXLNB VCL ZNF175 ZNF426	8 interacting genes: ALAS1 CDC42 KRTAP10-7 LPXN LZTR1 PSTPIP1 ZNF250 ZNF264
Entrez ID		9404	7728
HPRD ID		05651	03088
Ensembl ID		ENSG00000110031	ENSG00000105497
Uniprot IDs		B7Z5P7 O60711	Q9Y473
PDB IDs		1X3H 4XEF 4XEK 4XEV
Enriched GO Terms of Interacting Partners?
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