TCL1A and PRTFDC1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TCL1A	PRTFDC1
Description		T cell leukemia/lymphoma 1A	phosphoribosyl transferase domain containing 1
Image
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Cytosol Protein-containing Complex
	Molecular Function	Protein Binding Protein Kinase Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Binding Protein Homodimerization Activity
	Biological Process	Multicellular Organism Development Positive Regulation Of Cell Proliferation Positive Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Protein Complex Assembly Positive Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Apoptotic Process Cellular Response To Tumor Necrosis Factor Positive Regulation Of Protein Serine/threonine Kinase Activity	Purine Ribonucleoside Salvage Guanine Salvage GMP Catabolic Process
Pathways
Drugs
Diseases
GWAS		Adverse response to aromatase inhibitors ( 20876420) Mosaic loss of chromosome Y ( 27064253) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)	Diisocyanate-induced asthma ( 25918132) Granulocyte count ( 27863252) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Intraocular pressure ( 29617998) Lymphocyte counts ( 27863252) Metabolite levels (Pyroglutamine) ( 23934736) Monocyte count ( 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Obesity-related traits ( 23251661) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Platelet count ( 27863252) Plateletcrit ( 27863252) Post-traumatic stress disorder ( 25456346) Red cell distribution width ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 27863252)
Interacting Genes		23 interacting genes: AKT1 AKT2 AKT3 ATM CADPS CALCOCO2 CARD9 CEP55 DNMT3A FLACC1 GOLGA2 H2AW LNX2 LSM3 NTAQ1 PRTFDC1 TCF4 TP53BP2 TRAF1 TTC33 TXLNA TXLNB WDR47	14 interacting genes: DTNB EEF2KMT EPM2AIP1 EWSR1 FLAD1 GNPDA1 HPRT1 LGALS9B MCMBP NIF3L1 RAB18 STAT5A TCL1A TMEM14B
Entrez ID		8115	56952
HPRD ID		01744	17917
Ensembl ID		ENSG00000100721	ENSG00000099256
Uniprot IDs		A0A024R6G5 P56279	Q9NRG1
PDB IDs		1JSG	2JBH
Enriched GO Terms of Interacting Partners?
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