TCL1A and CADPS

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TCL1A	CADPS
Description		T cell leukemia/lymphoma 1A	calcium dependent secretion activator
Image
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Cytosol Protein-containing Complex	Cytosol Cell Junction Presynapse Glutamatergic Synapse Neuronal Dense Core Vesicle Membrane
	Molecular Function	Protein Binding Protein Kinase Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity	Protein Binding Lipid Binding Protein Kinase Binding Metal Ion Binding
	Biological Process	Multicellular Organism Development Positive Regulation Of Cell Proliferation Positive Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Protein Complex Assembly Positive Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Apoptotic Process Cellular Response To Tumor Necrosis Factor Positive Regulation Of Protein Serine/threonine Kinase Activity	Exocytosis Protein Transport Synaptic Vesicle Exocytosis Positive Regulation Of Exocytosis Dense Core Granule Exocytosis
Pathways
Drugs			Calcium Citrate Calcium Phosphate
Diseases
GWAS		Adverse response to aromatase inhibitors ( 20876420) Mosaic loss of chromosome Y ( 27064253) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)	Autism spectrum disorder ( 30804558) Breast size ( 22747683 27182965) Cognitive decline rate in late mild cognitive impairment ( 26252872) Economic and political preferences (environmentalism) ( 22566634) Hand grip strength ( 29691431) Lung function (FEV1/FVC) ( 30061609) Metabolite levels (X-11787) ( 23934736) Obsessive-compulsive symptoms ( 26859814) Optic disc size ( 31809533) Pre-treatment viral load in HIV-1 infection ( 31219150) QT interval (sulfonylurea treatment interaction) ( 27958378) Risk-taking tendency (4-domain principal component model) ( 30643258) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Trunk fat mass ( 28552196)
Interacting Genes		23 interacting genes: AKT1 AKT2 AKT3 ATM CADPS CALCOCO2 CARD9 CEP55 DNMT3A FLACC1 GOLGA2 H2AW LNX2 LSM3 NTAQ1 PRTFDC1 TCF4 TP53BP2 TRAF1 TTC33 TXLNA TXLNB WDR47	15 interacting genes: C17orf67 DMD DNAJC5 DRD2 FAM161A FAM9B KIAA1549 LUC7L2 PIP5K1A SDCBP SHFL TCL1A TTLL10 ZNF572 ZNF688
Entrez ID		8115	8618
HPRD ID		01744	05236
Ensembl ID		ENSG00000100721	ENSG00000163618
Uniprot IDs		A0A024R6G5 P56279	F1T0E5 Q9ULU8
PDB IDs		1JSG	1WI1
Enriched GO Terms of Interacting Partners?
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