ZYG11B and SH2D2A

		ZYG11B	SH2D2A
Description		zyg-11 family member B, cell cycle regulator	SH2 domain containing 2A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cul2-RING Ubiquitin Ligase Complex	Cytoplasm Cytosol
	Molecular Function		SH3/SH2 Adaptor Activity Protein Binding SH3 Domain Binding Signaling Adaptor Activity
	Biological Process	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process	Angiogenesis Signal Transduction Cell Proliferation Positive Regulation Of Signal Transduction Cell Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway
Pathways			VEGFA-VEGFR2 Pathway
Drugs
Diseases
GWAS			Platelet count ( 27863252) SjÃ¶gren's syndrome ( 28076899)
Interacting Genes		13 interacting genes: ARPC2 ASPA BTBD2 BTF3L4 CFL2 CUL2 ELOB ELOC NDC1 OSBPL9 SH2D2A TLR6 UCK2	29 interacting genes: APPL1 ARID5A CRK DAPK1 EGFR ERBB2 ITK KDR LCK LINC02875 LNX1 LRRFIP1 LRRK1 MAP3K2 MAPK7 MFHAS1 NAA16 PLCG1 PPP1R21 SOCS3 SPTB STAT3 SYK TSC1 TXK VCP ZHX3 ZSCAN1 ZYG11B
Entrez ID		79699	9047
HPRD ID		13356	05152
Ensembl ID		ENSG00000162378	ENSG00000027869
Uniprot IDs		A8DPD7 B4DK95 Q9C0D3	Q5UBZ2 Q5UBZ3 Q9NP31
PDB IDs
Enriched GO Terms of Interacting Partners?
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