SH2D2A and ARID5A

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

Data Source:
BioGRID (two hybrid)

		SH2D2A	ARID5A
Description		SH2 domain containing 2A	AT-rich interaction domain 5A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Nucleoplasm Nucleolus
	Molecular Function	SH3/SH2 Adaptor Activity Protein Binding SH3 Domain Binding Signaling Adaptor Activity	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Transcription Corepressor Activity RNA Binding Protein Binding Transcription Factor Binding Estrogen Receptor Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding Androgen Receptor Binding
	Biological Process	Angiogenesis Signal Transduction Cell Proliferation Positive Regulation Of Signal Transduction Cell Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Innate Immune Response Negative Regulation Of Transcription, DNA-templated Cellular Response To Estrogen Stimulus
Pathways		VEGFA-VEGFR2 Pathway
Drugs
Diseases
GWAS		Platelet count ( 27863252) SjÃ¶gren's syndrome ( 28076899)	Eosinophil counts ( 27863252) Eosinophil percentage of white cells ( 27863252) Event-related brain oscillations ( 21184583)
Interacting Genes		29 interacting genes: APPL1 ARID5A CRK DAPK1 EGFR ERBB2 ITK KDR LCK LINC02875 LNX1 LRRFIP1 LRRK1 MAP3K2 MAPK7 MFHAS1 NAA16 PLCG1 PPP1R21 SOCS3 SPTB STAT3 SYK TSC1 TXK VCP ZHX3 ZSCAN1 ZYG11B	19 interacting genes: AR ATXN1 CKS1B DAB1 DAZAP2 ESR2 GOLGA2 KRT40 KRTAP12-2 KRTAP12-4 MDFI PNMA1 RARA RBPMS RHOXF2 RXRA SH2D2A SOX5 THRA
Entrez ID		9047	10865
HPRD ID		05152	12481
Ensembl ID		ENSG00000027869	ENSG00000196843
Uniprot IDs		Q5UBZ2 Q5UBZ3 Q9NP31	Q03989
PDB IDs
Enriched GO Terms of Interacting Partners?
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