C1QA and SLC25A47

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		C1QA	SLC25A47
Description		complement C1q A chain	solute carrier family 25 member 47
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Complement Component C1 Complex Cell Synapse Collagen-containing Extracellular Matrix Postsynapse	Mitochondrial Inner Membrane Integral Component Of Membrane
	Molecular Function	Amyloid-beta Binding Protein Binding	Acyl Carnitine Transmembrane Transporter Activity
	Biological Process	Microglial Cell Activation Complement Activation Complement Activation, Classical Pathway Cell-cell Signaling Aging Response To Iron Ion Viral Process Neuron Remodeling Regulation Of Complement Activation Innate Immune Response Astrocyte Activation Synapse Organization Synapse Pruning Complement-mediated Synapse Pruning Vertebrate Eye-specific Patterning Positive Regulation Of Neuron Death	Acyl Carnitine Transport Amino Acid Transport Acyl Carnitine Transmembrane Transport
Pathways		Initial triggering of complement Classical antibody-mediated complement activation Regulation of Complement cascade
Drugs		Cetuximab Etanercept Adalimumab Abciximab Gemtuzumab ozogamicin Trastuzumab Rituximab Basiliximab Muromonab Ibritumomab tiuxetan Tositumomab Alemtuzumab Alefacept Efalizumab Natalizumab Palivizumab Daclizumab Bevacizumab
Diseases		Classic complement pathway component defects, including the following eight diseases: C1q alpha-chain deficiency; C1q beta-chain deficiency; C1q gamma-chain deficiency; C1r deficiency; C1s deficiency; C2 deficiency; C3 deficiency; C4 deficiency
GWAS
Interacting Genes		28 interacting genes: APCS BAG6 C1QB C1QBP C1QC C1R C1S CD93 COL2A1 CR1 CRP CSPG4 DCN FN1 GNPNAT1 HIPK3 HRG HSPB2 NLGN3 PIAS2 PPP1CA PPP1CC PTX3 RHOA SGTA SLC25A47 UBQLN1 UBQLN2	2 interacting genes: C1QA DIABLO
Entrez ID		712	283600
HPRD ID		00393	16620
Ensembl ID		ENSG00000173372	ENSG00000140107
Uniprot IDs		A0A024RAG6 P02745	A0A024R6H7 Q6Q0C1
PDB IDs		1PK6 2JG8 2JG9 2WNU 2WNV 5HKJ 5HZF 6FCZ
Enriched GO Terms of Interacting Partners?
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