SLC25A47 and C1QA

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		SLC25A47	C1QA
Description		solute carrier family 25 member 47	complement C1q A chain
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Integral Component Of Membrane	Extracellular Region Collagen Trimer Complement Component C1 Complex Cell Synapse Collagen-containing Extracellular Matrix Postsynapse
	Molecular Function	Acyl Carnitine Transmembrane Transporter Activity	Amyloid-beta Binding Protein Binding
	Biological Process	Acyl Carnitine Transport Amino Acid Transport Acyl Carnitine Transmembrane Transport	Microglial Cell Activation Complement Activation Complement Activation, Classical Pathway Cell-cell Signaling Aging Response To Iron Ion Viral Process Neuron Remodeling Regulation Of Complement Activation Innate Immune Response Astrocyte Activation Synapse Organization Synapse Pruning Complement-mediated Synapse Pruning Vertebrate Eye-specific Patterning Positive Regulation Of Neuron Death
Pathways			Initial triggering of complement Classical antibody-mediated complement activation Regulation of Complement cascade
Drugs			Cetuximab Etanercept Adalimumab Abciximab Gemtuzumab ozogamicin Trastuzumab Rituximab Basiliximab Muromonab Ibritumomab tiuxetan Tositumomab Alemtuzumab Alefacept Efalizumab Natalizumab Palivizumab Daclizumab Bevacizumab
Diseases			Classic complement pathway component defects, including the following eight diseases: C1q alpha-chain deficiency; C1q beta-chain deficiency; C1q gamma-chain deficiency; C1r deficiency; C1s deficiency; C2 deficiency; C3 deficiency; C4 deficiency
GWAS
Interacting Genes		2 interacting genes: C1QA DIABLO	28 interacting genes: APCS BAG6 C1QB C1QBP C1QC C1R C1S CD93 COL2A1 CR1 CRP CSPG4 DCN FN1 GNPNAT1 HIPK3 HRG HSPB2 NLGN3 PIAS2 PPP1CA PPP1CC PTX3 RHOA SGTA SLC25A47 UBQLN1 UBQLN2
Entrez ID		283600	712
HPRD ID		16620	00393
Ensembl ID		ENSG00000140107	ENSG00000173372
Uniprot IDs		A0A024R6H7 Q6Q0C1	A0A024RAG6 P02745
PDB IDs			1PK6 2JG8 2JG9 2WNU 2WNV 5HKJ 5HZF 6FCZ
Enriched GO Terms of Interacting Partners?
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