ABCC8 and ENSA

Number of citations of the paper that reports this interaction (PubMedID 9653196)
14

Data Source:
HPRD (in vivo)

		ABCC8	ENSA
Description		ATP binding cassette subfamily C member 8	endosulfine alpha
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Inward Rectifying Potassium Channel Membrane Potassium Ion-transporting ATPase Complex	Nucleoplasm Cytoplasm
	Molecular Function	Potassium Channel Activity ATP Binding Sulfonylurea Receptor Activity ATP-activated Inward Rectifier Potassium Channel Activity ATPase Activity Cation-transporting ATPase Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances Ion Channel Binding	Protein Phosphatase Inhibitor Activity Signaling Receptor Binding Protein Binding Ion Channel Inhibitor Activity Phosphatase Inhibitor Activity Potassium Channel Inhibitor Activity Protein Phosphatase Regulator Activity Protein Phosphatase 2A Binding
	Biological Process	Potassium Ion Transport Regulation Of Insulin Secretion Transmembrane Transport Potassium Ion Transmembrane Transport Inorganic Cation Transmembrane Transport	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Response To Nutrient Response To Glucose Negative Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Protein Dephosphorylation Regulation Of Insulin Secretion Cell Division
Pathways		ATP sensitive Potassium channels Regulation of insulin secretion Defective ABCC8 can cause hypoglycemias and hyperglycemias	MASTL Facilitates Mitotic Progression MASTL Facilitates Mitotic Progression
Drugs		ATP Glimepiride Chlorpropamide Nateglinide Tolazamide Repaglinide Glyburide Glipizide Gliclazide Tolbutamide Gliquidone Mitiglinide Glycodiazine
Diseases		Permanent neonatal diabetes mellitus (PNDM) Transient neonatal diabetes mellitus (TNDM)
GWAS		Alcohol dependence symptom count ( 29460428) Body mass index ( 26426971) Gout ( 22179738) Mean arterial pressure ( 27618448) Metabolite levels ( 23823483) Type 2 diabetes ( 29632382) Type 2 diabetes (adjusted for BMI) ( 29632382)	Albumin-globulin ratio ( 29403010) Chronotype ( 30696823) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Lung function (FEV1) ( 26635082) Lung function (FVC) ( 26635082) Monocyte count ( 29403010 27863252) Monocyte percentage of white cells ( 27863252) Morning person ( 30696823) Neutrophil percentage of granulocytes ( 27863252) Non-albumin protein levels ( 29403010) Pericardial adipose tissue adjusted for height and weight ( 27918534) Rhegmatogenous retinal detachment ( 23585552) Sum eosinophil basophil counts ( 27863252) Urate levels ( 31578528)
Interacting Genes		4 interacting genes: CRYBB1 ENSA KCNJ11 KCNJ8	11 interacting genes: ABCC8 ACD ARIH2 ENO2 GORASP1 KCTD15 POT1 PSEN1 RAP2A SNCA SRPK2
Entrez ID		6833	2029
HPRD ID		02741	11927
Ensembl ID		ENSG00000006071	ENSG00000143420
Uniprot IDs		Q09428	O43768
PDB IDs		6C3O 6C3P
Enriched GO Terms of Interacting Partners?
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