STX4 and STXBP3

Number of citations of the paper that reports this interaction (PubMedID 10194441)
24

Data Source:
HPRD (in vitro)

		STX4	STXBP3
Description		syntaxin 4	syntaxin binding protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Storage Vacuole Extracellular Space Endosome Vacuole Trans-Golgi Network Cytosol Plasma Membrane Synaptic Vesicle Cell Surface Endomembrane System Membrane Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium Phagocytic Vesicle Membrane SNARE Complex Myelin Sheath Adaxonal Region Somatodendritic Compartment Specific Granule Presynaptic Membrane Dendritic Spine Lateral Loop Synapse Perinuclear Region Of Cytoplasm Presynaptic Active Zone Membrane Extracellular Exosome Postsynapse Glutamatergic Synapse	Cell Cytosol Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Platelet Alpha Granule Specific Granule Phagocytic Vesicle Extracellular Exosome Tertiary Granule Presynapse
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Sphingomyelin Phosphodiesterase Activator Activity	Protein Binding Syntaxin-1 Binding Syntaxin Binding Protein-containing Complex Binding
	Biological Process	Intracellular Protein Transport Exocytosis Post-Golgi Vesicle-mediated Transport Vesicle Fusion Positive Regulation Of Cell Proliferation Regulation Of Exocytosis Cytokine-mediated Signaling Pathway Positive Regulation Of Cell Migration Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cellular Response To Oxidative Stress SNARE Complex Assembly Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Catalytic Activity Positive Regulation Of Eosinophil Degranulation Positive Regulation Of Cell Adhesion Vesicle Docking Organelle Fusion Positive Regulation Of Chemotaxis Positive Regulation Of Immunoglobulin Secretion Long-term Synaptic Potentiation Cellular Response To Interferon-gamma Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Protein Localization To Plasma Membrane Cornified Envelope Assembly Vesicle Fusion With Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Membrane Positive Regulation Of Protein Localization To Cell Surface	Cellular Glucose Homeostasis Vesicle Docking Involved In Exocytosis Brain Development Protein To Membrane Docking Insulin Secretion Response To Insulin Neutrophil Degranulation Negative Regulation Of Calcium Ion-dependent Exocytosis Negative Regulation Of Glucose Import Platelet Aggregation Cellular Response To Interferon-gamma
Pathways		Disinhibition of SNARE formation ER-Phagosome pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane trans-Golgi Network Vesicle Budding Other interleukin signaling	Disinhibition of SNARE formation Translocation of SLC2A4 (GLUT4) to the plasma membrane
Drugs
Diseases
GWAS		Response to metformin (IC50) ( 28173075)	Fat distribution (HIV) ( 21897333)
Interacting Genes		48 interacting genes: ACTB BET1 CYBRD1 DLG1 DNAJC5 EMD GIMAP5 GOSR2 ITSN2 LLGL1 LMNA NAPA NAPB NSF PSMA3 RAB11A RAB4A RAB5A SCRIB SEC22A SEPTIN5 SH3GLB2 SNAP23 SNAP25 SNAP29 SNAP47 STX16 STX3 STX5 STX8 STXBP3 STXBP4 STXBP5 STXBP6 SYT1 SYT4 SYT7 TXLNA TXLNB TXLNG VAMP1 VAMP2 VAMP3 VAMP4 VAMP7 VAMP8 VAPB VTI1B	14 interacting genes: DDX20 GEMIN2 GEMIN4 GEMIN5 PRKCA RPL3 SMN1 SNRPB SNRPD2 SNRPD3 SNTG1 STX4 STXBP2 VAMP2
Entrez ID		6810	6814
HPRD ID		01722	10517
Ensembl ID		ENSG00000103496	ENSG00000116266
Uniprot IDs		B7Z425 Q12846	O00186
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?