STXBP3 and RPL3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		STXBP3	RPL3
Description		syntaxin binding protein 3	ribosomal protein L3
Image		No pdb structure
GO Annotations	Cellular Component	Cell Cytosol Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Platelet Alpha Granule Specific Granule Phagocytic Vesicle Extracellular Exosome Tertiary Granule Presynapse	Nucleus Nucleolus Cytoplasm Cytosol Focal Adhesion Cytosolic Large Ribosomal Subunit Protein-containing Complex Synapse Extracellular Exosome
	Molecular Function	Protein Binding Syntaxin-1 Binding Syntaxin Binding Protein-containing Complex Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding 5S RRNA Binding
	Biological Process	Cellular Glucose Homeostasis Vesicle Docking Involved In Exocytosis Brain Development Protein To Membrane Docking Insulin Secretion Response To Insulin Neutrophil Degranulation Negative Regulation Of Calcium Ion-dependent Exocytosis Negative Regulation Of Glucose Import Platelet Aggregation Cellular Response To Interferon-gamma	Ribosomal Large Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Cellular Response To Interleukin-4
Pathways		Disinhibition of SNARE formation Translocation of SLC2A4 (GLUT4) to the plasma membrane	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs			Alpha-Hydroxy-Beta-Phenyl-Propionic Acid Omacetaxine mepesuccinate Anisomycin Puromycin Xanthinol
Diseases
GWAS		Fat distribution (HIV) ( 21897333)	Crohn's disease ( 28067908) Factor VIII levels ( 30586737) Inflammatory bowel disease ( 28067908) Primary biliary cholangitis ( 28425483) Primary biliary cirrhosis ( 22961000) Ulcerative colitis ( 28067908) vWF levels ( 30586737)
Interacting Genes		14 interacting genes: DDX20 GEMIN2 GEMIN4 GEMIN5 PRKCA RPL3 SMN1 SNRPB SNRPD2 SNRPD3 SNTG1 STX4 STXBP2 VAMP2	8 interacting genes: CREBBP MTNR1A NDRG1 NUMB SIK1 STXBP3 SUMO2 TRAF6
Entrez ID		6814	6122
HPRD ID		10517	16042
Ensembl ID		ENSG00000116266	ENSG00000100316
Uniprot IDs		O00186	B3KS36 P39023 Q96QL0
PDB IDs			4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
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