SSX1 and LHX4

Number of citations of the paper that reports this interaction (PubMedID 17667940)
13

Data Source:
BioGRID (two hybrid)

		SSX1	LHX4
Description		SSX family member 1	LIM homeobox 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nuclear Chromatin Nucleus
	Molecular Function	Nucleic Acid Binding Transcription Corepressor Activity Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Methyl-CpG Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription	Placenta Development Motor Neuron Axon Guidance Animal Organ Morphogenesis Medial Motor Column Neuron Differentiation Neuron Differentiation Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Regulation of expression of SLITs and ROBOs
Drugs
Diseases		Synovial sarcoma	Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS
Interacting Genes		3 interacting genes: FUBP3 LHX4 MAGEC2	22 interacting genes: ADAMTSL4 AXIN1 CHCHD2 FDX2 GOLGA2 IFT172 IKZF1 KRT38 KRT40 LDB2 LONRF1 NRF1 ORC6 SH2D1A SNRNP25 SSX1 TCAP TCF4 TP53BP2 TXNDC5 UBQLN1 USP2
Entrez ID		6756	89884
HPRD ID		02428	03686
Ensembl ID		ENSG00000126752	ENSG00000121454
Uniprot IDs		Q16384	A0A0S2Z5S4 Q969G2
PDB IDs			5HOD
Enriched GO Terms of Interacting Partners?
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