SNTB2 and SCN4A

Number of citations of the paper that reports this interaction (PubMedID 9412493)
97

Data Source:
HPRD (in vivo)

		SNTB2	SCN4A
Description		syntrophin beta 2	sodium voltage-gated channel alpha subunit 4
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GO Annotations	Cellular Component	Intracellular Cytoplasm Microtubule Focal Adhesion Dystrophin-associated Glycoprotein Complex Membrane Transport Vesicle Membrane Protein-containing Complex Synapse	Voltage-gated Sodium Channel Complex Plasma Membrane Integral Component Of Plasma Membrane Axon
	Molecular Function	RNA Binding Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding	Voltage-gated Ion Channel Activity Voltage-gated Sodium Channel Activity Cation Channel Activity Protein Binding
	Biological Process		Sodium Ion Transport Muscle Contraction Neuronal Action Potential Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Membrane Depolarization During Action Potential Regulation Of Skeletal Muscle Contraction By Action Potential
Pathways			Interaction between L1 and Ankyrins Phase 0 - rapid depolarisation
Drugs			Lidocaine Valproic Acid Diclofenac Propofol Zonisamide Flecainide Brivaracetam Chloroxylenol Parachlorophenol
Diseases			Hyperkalemic periodic paralysis (HyperPP) Potassium-aggravated myotonias (PAMs), including: Myotonia fluctuans; Myotonia permanens; Acetazolamide responsive myotonia Hypokalemic periodic paralysis (HypoPP) Paramyotonia congenita (PMC) Congenital myasthenic syndrome
GWAS		Body mass index ( 26426971) Logical memory (delayed recall) in normal cognition ( 29274321)	Height ( 28552196 31562340)
Interacting Genes		16 interacting genes: ABCA1 ADGRB1 ADRA1D DGKZ DMD DTNA ERBB4 KCNJ12 MAST1 MAST2 PTEN PTPRN SCN4A SCN5A UBC UTRN	10 interacting genes: CALM1 DLG1 DLG2 DLG3 ERBIN PATJ SLC9A3R1 SNTA1 SNTB1 SNTB2
Entrez ID		6645	6329
HPRD ID		02491	04912
Ensembl ID		ENSG00000168807	ENSG00000007314
Uniprot IDs		A0A024R732 Q13425	P35499
PDB IDs		2VRF	6AGF 6MBA 6MC9
Enriched GO Terms of Interacting Partners?
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