SCN4A and SNTB2

Number of citations of the paper that reports this interaction (PubMedID 9412493)
97

Data Source:
HPRD (in vivo)

		SCN4A	SNTB2
Description		sodium voltage-gated channel alpha subunit 4	syntrophin beta 2
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GO Annotations	Cellular Component	Voltage-gated Sodium Channel Complex Plasma Membrane Integral Component Of Plasma Membrane Axon	Intracellular Cytoplasm Microtubule Focal Adhesion Dystrophin-associated Glycoprotein Complex Membrane Transport Vesicle Membrane Protein-containing Complex Synapse
	Molecular Function	Voltage-gated Ion Channel Activity Voltage-gated Sodium Channel Activity Cation Channel Activity Protein Binding	RNA Binding Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding
	Biological Process	Sodium Ion Transport Muscle Contraction Neuronal Action Potential Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Membrane Depolarization During Action Potential Regulation Of Skeletal Muscle Contraction By Action Potential
Pathways		Interaction between L1 and Ankyrins Phase 0 - rapid depolarisation
Drugs		Lidocaine Valproic Acid Diclofenac Propofol Zonisamide Flecainide Brivaracetam Chloroxylenol Parachlorophenol
Diseases		Hyperkalemic periodic paralysis (HyperPP) Potassium-aggravated myotonias (PAMs), including: Myotonia fluctuans; Myotonia permanens; Acetazolamide responsive myotonia Hypokalemic periodic paralysis (HypoPP) Paramyotonia congenita (PMC) Congenital myasthenic syndrome
GWAS		Height ( 28552196 31562340)	Body mass index ( 26426971) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		10 interacting genes: CALM1 DLG1 DLG2 DLG3 ERBIN PATJ SLC9A3R1 SNTA1 SNTB1 SNTB2	16 interacting genes: ABCA1 ADGRB1 ADRA1D DGKZ DMD DTNA ERBB4 KCNJ12 MAST1 MAST2 PTEN PTPRN SCN4A SCN5A UBC UTRN
Entrez ID		6329	6645
HPRD ID		04912	02491
Ensembl ID		ENSG00000007314	ENSG00000168807
Uniprot IDs		P35499	A0A024R732 Q13425
PDB IDs		6AGF 6MBA 6MC9	2VRF
Enriched GO Terms of Interacting Partners?
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