SCN4A and PATJ

Number of citations of the paper that reports this interaction (PubMedID 16637659)
25

Data Source:
HPRD (in vitro)

		SCN4A	PATJ
Description		sodium voltage-gated channel alpha subunit 4	PATJ crumbs cell polarity complex component
Image			No pdb structure
GO Annotations	Cellular Component	Voltage-gated Sodium Channel Complex Plasma Membrane Integral Component Of Plasma Membrane Axon	Centrosome Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cell Junction Centriolar Satellite Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Voltage-gated Ion Channel Activity Voltage-gated Sodium Channel Activity Cation Channel Activity Protein Binding	Protein Binding
	Biological Process	Sodium Ion Transport Muscle Contraction Neuronal Action Potential Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Membrane Depolarization During Action Potential Regulation Of Skeletal Muscle Contraction By Action Potential	Intracellular Signal Transduction Bicellular Tight Junction Assembly
Pathways		Interaction between L1 and Ankyrins Phase 0 - rapid depolarisation
Drugs		Lidocaine Valproic Acid Diclofenac Propofol Zonisamide Flecainide Brivaracetam Chloroxylenol Parachlorophenol
Diseases		Hyperkalemic periodic paralysis (HyperPP) Potassium-aggravated myotonias (PAMs), including: Myotonia fluctuans; Myotonia permanens; Acetazolamide responsive myotonia Hypokalemic periodic paralysis (HypoPP) Paramyotonia congenita (PMC) Congenital myasthenic syndrome
GWAS		Height ( 28552196 31562340)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30582445) Excessive daytime sleepiness ( 27992416) Sleep traits (multi-trait analysis) ( 27992416) Type 2 diabetes ( 30297969)
Interacting Genes		10 interacting genes: CALM1 DLG1 DLG2 DLG3 ERBIN PATJ SLC9A3R1 SNTA1 SNTB1 SNTB2	28 interacting genes: ADGRB1 ASIC3 CACNG2 CLDN1 CNKSR2 CRB3 CRIPT DDX18 GLS2 GRIN2A GRIN2B GRIN2C GRIN2D KCNA4 KCNJ10 KCNJ15 KCNJ2 KIF1B MAPK12 MPP5 NLGN2 NRXN2 PARD3 PAX6 PRDM16 SCN4A SCN5A TJP3
Entrez ID		6329	10207
HPRD ID		04912	04434
Ensembl ID		ENSG00000007314	ENSG00000132849
Uniprot IDs		P35499
PDB IDs		6AGF 6MBA 6MC9
Enriched GO Terms of Interacting Partners?
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