AEN and MBNL1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		AEN	MBNL1
Description		apoptosis enhancing nuclease	muscleblind like splicing regulator 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule
	Molecular Function	Nucleic Acid Binding Exonuclease Activity Protein Binding	Regulatory Region RNA Binding RNA Binding Double-stranded RNA Binding Protein Binding Metal Ion Binding
	Biological Process	DNA Catabolic Process, Exonucleolytic RNA Catabolic Process Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Viral Genome Replication Defense Response To Virus	Regulation Of Alternative MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Processing Nervous System Development RNA Splicing Embryonic Limb Morphogenesis Regulation Of RNA Splicing Myoblast Differentiation
Pathways
Drugs
Diseases
GWAS		Dupuytren's disease ( 28886342) Night sleep phenotypes ( 27126917)	Blond vs. brown/black hair color ( 30531825) End-stage renal disease ( 29885931) HDL cholesterol ( 30275531) Heel bone mineral density ( 30598549) Infantile hypertrophic pyloric stenosis ( 22306654) Male-pattern baldness ( 27182965) Prostate cancer ( 29892016) Type 2 diabetes ( 30054458 30297969)
Interacting Genes		34 interacting genes: CRTC3 EMD EXOSC8 GNPTAB HOMEZ IKZF1 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SPOP SSX2IP TLE5 TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF473	10 interacting genes: ABI3BP AEN APP BIN1 DAB1 FBXO7 IDH3A ITSN2 TLE5 ZNHIT3
Entrez ID		64782	4154
HPRD ID		08573	07355
Ensembl ID		ENSG00000181026	ENSG00000152601
Uniprot IDs		Q8WTP8	A0A0A0MQX8 C9JP00 Q86VM6 Q9NR56
PDB IDs			3D2N 3D2Q 3D2S 5U6H 5U6L 5U9B
Enriched GO Terms of Interacting Partners?
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