AEN and ZBTB43

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		AEN	ZBTB43
Description		apoptosis enhancing nuclease	zinc finger and BTB domain containing 43
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Membrane	Nuclear Chromatin
	Molecular Function	Nucleic Acid Binding Exonuclease Activity Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding
	Biological Process	DNA Catabolic Process, Exonucleolytic RNA Catabolic Process Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Viral Genome Replication Defense Response To Virus	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Dupuytren's disease ( 28886342) Night sleep phenotypes ( 27126917)	BMI (adjusted for smoking behaviour) ( 28443625) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Eyebrow thickness ( 26926045)
Interacting Genes		34 interacting genes: CRTC3 EMD EXOSC8 GNPTAB HOMEZ IKZF1 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SPOP SSX2IP TLE5 TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF473	19 interacting genes: AEN AP1M1 ARR3 ARRB1 BDP1 DIP2A ELOA2 FAM161A LMO1 LMO3 LMO4 LNX1 MCM10 MORF4L2 PSMD3 SYT6 TRAF2 ZBTB24 ZNF417
Entrez ID		64782	23099
HPRD ID		08573	08346
Ensembl ID		ENSG00000181026	ENSG00000169155
Uniprot IDs		Q8WTP8	O43298
PDB IDs			2CSH
Enriched GO Terms of Interacting Partners?
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