MBNL1 and AEN

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MBNL1	AEN
Description		muscleblind like splicing regulator 1	apoptosis enhancing nuclease
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule	Nucleus Nucleoplasm Nucleolus Nuclear Membrane
	Molecular Function	Regulatory Region RNA Binding RNA Binding Double-stranded RNA Binding Protein Binding Metal Ion Binding	Nucleic Acid Binding Exonuclease Activity Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Processing Nervous System Development RNA Splicing Embryonic Limb Morphogenesis Regulation Of RNA Splicing Myoblast Differentiation	DNA Catabolic Process, Exonucleolytic RNA Catabolic Process Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Viral Genome Replication Defense Response To Virus
Pathways
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) End-stage renal disease ( 29885931) HDL cholesterol ( 30275531) Heel bone mineral density ( 30598549) Infantile hypertrophic pyloric stenosis ( 22306654) Male-pattern baldness ( 27182965) Prostate cancer ( 29892016) Type 2 diabetes ( 30054458 30297969)	Dupuytren's disease ( 28886342) Night sleep phenotypes ( 27126917)
Interacting Genes		10 interacting genes: ABI3BP AEN APP BIN1 DAB1 FBXO7 IDH3A ITSN2 TLE5 ZNHIT3	34 interacting genes: CRTC3 EMD EXOSC8 GNPTAB HOMEZ IKZF1 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SPOP SSX2IP TLE5 TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF473
Entrez ID		4154	64782
HPRD ID		07355	08573
Ensembl ID		ENSG00000152601	ENSG00000181026
Uniprot IDs		A0A0A0MQX8 C9JP00 Q86VM6 Q9NR56	Q8WTP8
PDB IDs		3D2N 3D2Q 3D2S 5U6H 5U6L 5U9B
Enriched GO Terms of Interacting Partners?
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