PRDM14 and BEX2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PRDM14	BEX2
Description		PR/SET domain 14	brain expressed X-linked 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding Methyltransferase Activity Chromatin DNA Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Morphogenesis Cell Fate Specification Inner Cell Mass Cell Fate Commitment Germ Cell Development Embryo Implantation Fertilization Germ-line Stem Cell Population Maintenance Histone H3-R26 Methylation Somatic Stem Cell Population Maintenance Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of DNA Methylation Homeostasis Of Number Of Cells Within A Tissue Inactivation Of Paternal X Chromosome Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Stem Cell Population Maintenance	Apoptotic Process Cell Cycle Regulation Of Apoptotic Process Regulation Of Cell Cycle
Pathways		Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS		Schizophrenia ( 30285260) Testicular germ cell tumor ( 28604728 28604732 23666240)
Interacting Genes		32 interacting genes: AKAP9 ATPAF2 BAG4 BCAR3 BEX2 CASP8 CDCA7L CHEK2 DGCR6 EED EIF4E2 ERBB2 EZH2 GPATCH2L HEXIM2 HSPB7 ID3 IDH1 MIA3 NDUFB9 PALB2 PAX2 PLEKHF2 PRKAB2 PSMA1 PTPRJ RAD51D RBM10 RCOR3 SUZ12 TEKT4 TTC32	35 interacting genes: AURKA BCAR3 BLZF1 BRMS1 CALCOCO2 CCDC85B CEP70 FGFR2 FSD2 KRT15 KRT31 KRT38 KRT40 KRTAP10-8 KRTAP4-12 KRTAP5-9 LMO2 LZTS2 MAGEA11 MAGEA4 MIPOL1 MKRN3 NECAB2 OMP PIK3CA PNMA1 PPM1D PRDM14 PTPN11 SSX2IP TRAF1 TRAF2 TRIM27 TRIM42 ZDHHC17
Entrez ID		63978	84707
HPRD ID		11457	06484
Ensembl ID		ENSG00000147596	ENSG00000133134
Uniprot IDs		Q9GZV8	Q9BXY8
PDB IDs
Enriched GO Terms of Interacting Partners?
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