PRDM14 and HSPB7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PRDM14	HSPB7
Description		PR/SET domain 14	heat shock protein family B (small) member 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Cytoplasm Cajal Body Aggresome
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding Methyltransferase Activity Chromatin DNA Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding Protein C-terminus Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Morphogenesis Cell Fate Specification Inner Cell Mass Cell Fate Commitment Germ Cell Development Embryo Implantation Fertilization Germ-line Stem Cell Population Maintenance Histone H3-R26 Methylation Somatic Stem Cell Population Maintenance Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of DNA Methylation Homeostasis Of Number Of Cells Within A Tissue Inactivation Of Paternal X Chromosome Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Stem Cell Population Maintenance	Response To Unfolded Protein Heart Development Regulation Of Heart Contraction
Pathways		Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS		Schizophrenia ( 30285260) Testicular germ cell tumor ( 28604728 28604732 23666240)	Arterial stiffness index ( 31235810) Erectile dysfunction ( 30583798) Systolic blood pressure ( 28739976)
Interacting Genes		32 interacting genes: AKAP9 ATPAF2 BAG4 BCAR3 BEX2 CASP8 CDCA7L CHEK2 DGCR6 EED EIF4E2 ERBB2 EZH2 GPATCH2L HEXIM2 HSPB7 ID3 IDH1 MIA3 NDUFB9 PALB2 PAX2 PLEKHF2 PRKAB2 PSMA1 PTPRJ RAD51D RBM10 RCOR3 SUZ12 TEKT4 TTC32	10 interacting genes: APP CEP76 HSPB8 PLEKHF2 PRDM14 REL SF3B4 SYCE1 TCF4 TRIM23
Entrez ID		63978	27129
HPRD ID		11457	13684
Ensembl ID		ENSG00000147596	ENSG00000173641
Uniprot IDs		Q9GZV8	Q9UBY9
PDB IDs
Enriched GO Terms of Interacting Partners?
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