SH2D4A and TACC1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SH2D4A	TACC1
Description		SH2 domain containing 4A	transforming acidic coiled-coil containing protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Cytoplasm Microtubule Organizing Center Cytosol Membrane Midbody
	Molecular Function	Protein Binding Phosphatase Binding Signaling Adaptor Activity	Protein Binding Nuclear Receptor Binding Estrogen Receptor Binding Glucocorticoid Receptor Binding Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding
	Biological Process	Positive Regulation Of Signal Transduction Negative Regulation Of Phosphatase Activity	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Cell Proliferation Cerebral Cortex Development Cell Division Positive Regulation Of Nuclear Receptor Transcription Coactivator Activity
Pathways
Drugs
Diseases
GWAS		Smooth-surface caries ( 24556642) Urate levels in overweight individuals ( 25811787) Urinary albumin excretion rate in type 1 diabetes ( 24595857)	Blond vs. brown/black hair color ( 30531825) Chronic mountain sickness ( 31417607) Midgestational circulating levels of PBDEs ( 28235828)
Interacting Genes		44 interacting genes: ALAS1 CASK CCDC172 CDR2 CEP70 CEP76 DBNL FSD2 GOLGA2 GRB2 HCLS1 HMBOX1 IKZF1 KRT40 LDOC1 LZTS2 MAGEA11 MAGEA6 MTUS2 NECAB2 NINL NUTM1 OLIG1 PDE4DIP PNMA1 PPP1CB PSTPIP1 RINT1 SH3GL1 SKAP1 SORBS2 SORBS3 SPAG5 STAM2 STX11 TACC1 TFIP11 TRAF2 TRIM23 TRIM27 UBXN11 USHBP1 VPS52 ZBTB16	15 interacting genes: AURKA AURKB BTRC HTT ITSN2 KAT2A KDM1A LSM7 MEMO1 SH2D4A SNRPG STX5 TDRD7 THAP12 YEATS4
Entrez ID		63898	6867
HPRD ID		08340	10391
Ensembl ID		ENSG00000104611	ENSG00000147526
Uniprot IDs		Q9H788	E7EVI4 O75410 Q5HYH0
PDB IDs
Enriched GO Terms of Interacting Partners?
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