SH2D4A and DBNL

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		SH2D4A	DBNL
Description		SH2 domain containing 4A	drebrin like
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Golgi Membrane Ruffle Podosome Extracellular Region Cytoplasm Early Endosome Cytosol Actin Filament Plasma Membrane Cell Cortex Postsynaptic Density Lamellipodium Cell Junction Dendrite Site Of Polarized Growth Clathrin-coated Vesicle Membrane Cortical Actin Cytoskeleton Secretory Granule Lumen Perikaryon Postsynaptic Membrane Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Phosphatase Binding Signaling Adaptor Activity	Actin Binding Protein Binding Protein C-terminus Binding Enzyme Activator Activity Protein Domain Specific Binding Cadherin Binding Actin Filament Binding
	Biological Process	Positive Regulation Of Signal Transduction Negative Regulation Of Phosphatase Activity	Adaptive Immune Response Receptor-mediated Endocytosis Activation Of JUN Kinase Activity Synapse Assembly Rac Protein Signal Transduction Regulation Of Actin Filament Polymerization Neutrophil Degranulation Positive Regulation Of Axon Extension Neuron Projection Morphogenesis Positive Regulation Of Dendritic Spine Morphogenesis Podosome Assembly Ruffle Assembly Postsynaptic Actin Cytoskeleton Organization
Pathways			Caspase-mediated cleavage of cytoskeletal proteins Neurexins and neuroligins Neutrophil degranulation
Drugs
Diseases
GWAS		Smooth-surface caries ( 24556642) Urate levels in overweight individuals ( 25811787) Urinary albumin excretion rate in type 1 diabetes ( 24595857)	Blood protein levels ( 30072576)
Interacting Genes		44 interacting genes: ALAS1 CASK CCDC172 CDR2 CEP70 CEP76 DBNL FSD2 GOLGA2 GRB2 HCLS1 HMBOX1 IKZF1 KRT40 LDOC1 LZTS2 MAGEA11 MAGEA6 MTUS2 NECAB2 NINL NUTM1 OLIG1 PDE4DIP PNMA1 PPP1CB PSTPIP1 RINT1 SH3GL1 SKAP1 SORBS2 SORBS3 SPAG5 STAM2 STX11 TACC1 TFIP11 TRAF2 TRIM23 TRIM27 UBXN11 USHBP1 VPS52 ZBTB16	12 interacting genes: ACD CASP3 HOMER1 MAP4K1 NEURL4 POT1 SH2D4A SH3BP2 SYK TERF1 TERF2IP ZAP70
Entrez ID		63898	28988
HPRD ID		08340	06588
Ensembl ID		ENSG00000104611	ENSG00000136279
Uniprot IDs		Q9H788	B4DUF9 Q9UJU6
PDB IDs			1X67
Enriched GO Terms of Interacting Partners?
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