PATJ and SCN4A

Number of citations of the paper that reports this interaction (PubMedID 16637659)
25

Data Source:
HPRD (in vitro)

		PATJ	SCN4A
Description		PATJ crumbs cell polarity complex component	sodium voltage-gated channel alpha subunit 4
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cell Junction Centriolar Satellite Perinuclear Region Of Cytoplasm Extracellular Exosome	Voltage-gated Sodium Channel Complex Plasma Membrane Integral Component Of Plasma Membrane Axon
	Molecular Function	Protein Binding	Voltage-gated Ion Channel Activity Voltage-gated Sodium Channel Activity Cation Channel Activity Protein Binding
	Biological Process	Intracellular Signal Transduction Bicellular Tight Junction Assembly	Sodium Ion Transport Muscle Contraction Neuronal Action Potential Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Membrane Depolarization During Action Potential Regulation Of Skeletal Muscle Contraction By Action Potential
Pathways			Interaction between L1 and Ankyrins Phase 0 - rapid depolarisation
Drugs			Lidocaine Valproic Acid Diclofenac Propofol Zonisamide Flecainide Brivaracetam Chloroxylenol Parachlorophenol
Diseases			Hyperkalemic periodic paralysis (HyperPP) Potassium-aggravated myotonias (PAMs), including: Myotonia fluctuans; Myotonia permanens; Acetazolamide responsive myotonia Hypokalemic periodic paralysis (HypoPP) Paramyotonia congenita (PMC) Congenital myasthenic syndrome
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30582445) Excessive daytime sleepiness ( 27992416) Sleep traits (multi-trait analysis) ( 27992416) Type 2 diabetes ( 30297969)	Height ( 28552196 31562340)
Interacting Genes		28 interacting genes: ADGRB1 ASIC3 CACNG2 CLDN1 CNKSR2 CRB3 CRIPT DDX18 GLS2 GRIN2A GRIN2B GRIN2C GRIN2D KCNA4 KCNJ10 KCNJ15 KCNJ2 KIF1B MAPK12 MPP5 NLGN2 NRXN2 PARD3 PAX6 PRDM16 SCN4A SCN5A TJP3	10 interacting genes: CALM1 DLG1 DLG2 DLG3 ERBIN PATJ SLC9A3R1 SNTA1 SNTB1 SNTB2
Entrez ID		10207	6329
HPRD ID		04434	04912
Ensembl ID		ENSG00000132849	ENSG00000007314
Uniprot IDs			P35499
PDB IDs			6AGF 6MBA 6MC9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?