RRAS and ACY3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		RRAS	ACY3
Description		RAS related	aminoacylase 3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion Extracellular Exosome	Cytosol Apical Plasma Membrane Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Protein-containing Complex Binding	Molecular_function Aminoacylase Activity Protein Binding Hydrolase Activity, Acting On Ester Bonds Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides Identical Protein Binding Metal Ion Binding
	Biological Process	Leukocyte Differentiation Ras Protein Signal Transduction Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Cell Migration Positive Regulation Of Angiogenesis Regulation Of Protein Kinase B Signaling Face Morphogenesis Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Positive Regulation Of Vasculogenesis	Xenobiotic Metabolic Process Biological_process Viral Process
Pathways		SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration	Aflatoxin activation and detoxification
Drugs			L-Aspartic Acid
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163) Pulse pressure ( 27618447) Schizophrenia ( 25056061 29483656) Systolic blood pressure ( 27618447)	Serum metabolite levels ( 24625756) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes		15 interacting genes: ACY3 AFDN ARAF BCL2 EEF1A1 EPHB2 MRPL36 NAV2 NCK1 PPP2CA RAF1 RALGDS RASIP1 RASSF5 SOS1	14 interacting genes: AAMDC ASPA GORASP2 KRTAP10-3 KRTAP10-8 LNX1 MAP3K8 NEDD4L NOTCH2NLA PIAS2 PLEKHF2 PMM2 RARG RRAS
Entrez ID		6237	91703
HPRD ID		01299	12422
Ensembl ID		ENSG00000126458	ENSG00000132744
Uniprot IDs		A0A024QZF2 P10301	A0A024R5L2 Q96HD9
PDB IDs		2FN4
Enriched GO Terms of Interacting Partners?
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