KLHL12 and MED28

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KLHL12	MED28
Description		kelch like family member 12	mediator complex subunit 28
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytosol COPII Vesicle Coat COPII-coated ER To Golgi Transport Vesicle Cul3-RING Ubiquitin Ligase Complex Centriolar Satellite Intracellular Membrane-bounded Organelle	Nucleoplasm Membrane Mediator Complex Cortical Actin Cytoskeleton
	Molecular Function	Protein Binding Identical Protein Binding	Actin Binding Protein Binding
	Biological Process	Protein Monoubiquitination ER To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Wnt Signaling Pathway COPII Vesicle Coating Negative Regulation Of Canonical Wnt Signaling Pathway	Stem Cell Population Maintenance Negative Regulation Of Smooth Muscle Cell Differentiation
Pathways		Degradation of DVL	PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS
Interacting Genes		46 interacting genes: ARAF ATXN1 BAG6 C1QTNF2 CARD10 CCBE1 COL8A1 CPSF6 CRTC3 CUL3 DGCR6 DRD4 DVL2 DVL3 FBXL17 FGD2 FLNA GLYCTK INMT KHSRP KLHL2 KLHL3 LNX1 MED28 MPP1 MRPL10 MTNR1A NDC80 NTAQ1 PDGFRB PEA15 PEF1 PRR13 RIT1 RPP25L SDCBP SEC31A SNX20 SYNE4 TAOK2 TBC1D10C TTBK2 UBE2I VEGFB VTA1 ZBP1	16 interacting genes: CBY2 FYN GRB2 GRPEL1 KLHL12 LCK MAGEA11 MED30 MED8 MED9 NF2 PRMT6 PUF60 RAP1GDS1 SRC USHBP1
Entrez ID		59349	80306
HPRD ID		13925	14381
Ensembl ID		ENSG00000117153	ENSG00000118579
Uniprot IDs		Q53G59 Q9H7R2	Q9H204
PDB IDs		2VPJ
Enriched GO Terms of Interacting Partners?
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