KLHL12 and INMT

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KLHL12	INMT
Description		kelch like family member 12	indolethylamine N-methyltransferase
Image
GO Annotations	Cellular Component	Golgi Membrane Cytosol COPII Vesicle Coat COPII-coated ER To Golgi Transport Vesicle Cul3-RING Ubiquitin Ligase Complex Centriolar Satellite Intracellular Membrane-bounded Organelle	Cytoplasm Cytosol
	Molecular Function	Protein Binding Identical Protein Binding	Thioether S-methyltransferase Activity Protein Binding N-methyltransferase Activity Amine N-methyltransferase Activity S-adenosyl-L-methionine:beta-alanine N-methyltransferase Activity
	Biological Process	Protein Monoubiquitination ER To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Wnt Signaling Pathway COPII Vesicle Coating Negative Regulation Of Canonical Wnt Signaling Pathway	Amine Metabolic Process Response To Toxic Substance Methylation
Pathways		Degradation of DVL	Methylation of MeSeH for excretion
Drugs
Diseases
GWAS			Glucose homeostasis traits ( 25524916) Nephrolithiasis ( 22396660) Urolithiasis ( 30975718)
Interacting Genes		46 interacting genes: ARAF ATXN1 BAG6 C1QTNF2 CARD10 CCBE1 COL8A1 CPSF6 CRTC3 CUL3 DGCR6 DRD4 DVL2 DVL3 FBXL17 FGD2 FLNA GLYCTK INMT KHSRP KLHL2 KLHL3 LNX1 MED28 MPP1 MRPL10 MTNR1A NDC80 NTAQ1 PDGFRB PEA15 PEF1 PRR13 RIT1 RPP25L SDCBP SEC31A SNX20 SYNE4 TAOK2 TBC1D10C TTBK2 UBE2I VEGFB VTA1 ZBP1	2 interacting genes: KLHL12 LNX2
Entrez ID		59349	11185
HPRD ID		13925	06890
Ensembl ID		ENSG00000117153	ENSG00000241644
Uniprot IDs		Q53G59 Q9H7R2	O95050
PDB IDs		2VPJ	2A14
Enriched GO Terms of Interacting Partners?
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