RAB4A and RABAC1

Number of citations of the paper that reports this interaction (PubMedID 10329441)
20

Data Source:
HPRD (two hybrid)

		RAB4A	RABAC1
Description		RAB4A, member RAS oncogene family	Rab acceptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Endomembrane System Cytoplasmic Vesicle Membrane Early Endosome Membrane Vesicle Insulin-responsive Compartment Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome Postsynaptic Recycling Endosome Anchored Component Of Synaptic Vesicle Membrane	Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Integral Component Of Membrane Cell Junction
	Molecular Function	ATPase Activator Activity GTPase Activity Protein Binding GTP Binding GDP Binding Syntaxin Binding Ionotropic Glutamate Receptor Binding ATPase Binding	Protein Binding Protein C-terminus Binding Identical Protein Binding Proline-rich Region Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Intracellular Protein Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Positive Regulation Of ATPase Activity
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Synthesis of PIPs at the plasma membrane TBC/RABGAPs RAB geranylgeranylation MET receptor recycling
Drugs
Diseases
GWAS		Aging ( 22773346) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Mercury levels ( 26025379) Response to antidepressants in depression ( 27622933)
Interacting Genes		31 interacting genes: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 GDI2 GRIPAP1 HACE1 IDH3A KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABEP2 RABGAP1 RABGEF1 RBSN RUFY1 SOD2 STX4 TP53 VPS52 ZNF830	65 interacting genes: CMTM3 COQ8A CREB3 DUSP12 FAM160A2 FXR2 GDI1 HRAS HRG LMNA LNX1 MAD2L1 MCF2L MIEF2 NAT14 NDRG2 NIF3L1 NR3C2 NTAQ1 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP5 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RPS20 RRAS2 S100B SGK1 SNCA SNX1 SNX10 SNX11 SNX15 SPG21 SYT16 TNIP1 TRIM32 TSHR TUBB2A TXN2 VAMP2 VIM VTA1 WIPI2 ZFYVE21
Entrez ID		5867	10567
HPRD ID		01541	05375
Ensembl ID		ENSG00000168118	ENSG00000105404
Uniprot IDs		A0A024R3U9 A0A087WYT5 P20338	Q9UI14
PDB IDs		1YU9 1Z0K 2BMD 2BME
Enriched GO Terms of Interacting Partners?
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