RABAC1 and TSHR

Number of citations of the paper that reports this interaction (PubMedID 14604818)
4

Data Source:
HPRD (two hybrid)

		RABAC1	TSHR
Description		Rab acceptor 1	thyroid stimulating hormone receptor
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Integral Component Of Membrane Cell Junction	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Basolateral Plasma Membrane Receptor Complex
	Molecular Function	Protein Binding Protein C-terminus Binding Identical Protein Binding Proline-rich Region Binding	Thyroid-stimulating Hormone Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Signaling Receptor Activity Protein-containing Complex Binding
	Biological Process		Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Cell-cell Signaling Positive Regulation Of Cell Proliferation Hormone-mediated Signaling Pathway Thyroid-stimulating Hormone Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis Cellular Response To Glycoprotein Cellular Response To Thyrotropin-releasing Hormone
Pathways			Hormone ligand-binding receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Thyrotropin Alfa
Diseases			Congenital nongoitrous hypothyroidism (CHNG)
GWAS			Graves' disease ( 21841780 22922229) Hair morphology ( 19896111) Male sexual orientation ( 29217827) Maximal oxygen uptake response ( 25729143) Obstetric antiphospholipid syndrome ( 28424481) Optic nerve measurement (rim area) ( 20395239) Smooth-surface caries ( 24556642) Thyroid stimulating hormone levels ( 30367059) Tourette syndrome ( 30818990) Uric acid levels ( 21294900) Visceral fat ( 22589738)
Interacting Genes		65 interacting genes: CMTM3 COQ8A CREB3 DUSP12 FAM160A2 FXR2 GDI1 HRAS HRG LMNA LNX1 MAD2L1 MCF2L MIEF2 NAT14 NDRG2 NIF3L1 NR3C2 NTAQ1 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP5 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RPS20 RRAS2 S100B SGK1 SNCA SNX1 SNX10 SNX11 SNX15 SPG21 SYT16 TNIP1 TRIM32 TSHR TUBB2A TXN2 VAMP2 VIM VTA1 WIPI2 ZFYVE21	23 interacting genes: ADRB2 CALR CANX FLNB FN1 GNA11 GNA12 GNA13 GNAI1 GNAI2 GNAI3 GNAO1 GNAQ GNAS HSPA5 JAK1 JAK2 LHCGR PIK3R1 RABAC1 SCRIB STAT3 TSHB
Entrez ID		10567	7253
HPRD ID		05375	04537
Ensembl ID		ENSG00000105404	ENSG00000165409
Uniprot IDs		Q9UI14	A0A0A0MTJ0 P16473
PDB IDs			1XUM 2XWT 3G04
Enriched GO Terms of Interacting Partners?
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