LRRC4C and WHRN

Number of citations of the paper that reports this interaction (PubMedID 15590698)
79

Data Source:
HPRD (in vitro, two hybrid)

		LRRC4C	WHRN
Description		leucine rich repeat containing 4C	whirlin
Image
GO Annotations	Cellular Component	Extracellular Space Membrane Integral Component Of Membrane Cell Junction Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane	Photoreceptor Inner Segment Stereocilia Ankle Link Stereocilia Ankle Link Complex Cytoplasm Actin Filament Plasma Membrane Cell Junction Growth Cone Photoreceptor Connecting Cilium Stereocilium Stereocilium Tip Ciliary Basal Body Neuronal Cell Body Synapse Periciliary Membrane Compartment USH2 Complex
	Molecular Function	Protein Binding Cell Adhesion Molecule Binding Cell-cell Adhesion Mediator Activity	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Axonogenesis Modulation Of Chemical Synaptic Transmission Synaptic Membrane Adhesion	Retina Homeostasis Sensory Perception Of Sound Positive Regulation Of Gene Expression Cerebellar Purkinje Cell Layer Formation Establishment Of Protein Localization Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Sensory Perception Of Light Stimulus Auditory Receptor Cell Stereocilium Organization Inner Ear Receptor Cell Development Inner Ear Receptor Cell Stereocilium Organization Paranodal Junction Maintenance
Pathways
Drugs
Diseases			Usher syndrome (US) Deafness, autosomal recessive
GWAS		Blood protein levels ( 30072576) Cerebellum cortex volume ( 31530798) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Cerebrospinal fluid p-tau levels ( 29274321) Diastolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) General risk tolerance (MTAG) ( 30643258) Iris color (L* coordinate) ( 30895295) Mosquito bite size ( 28199695) Myopia ( 27182965) Osteoporosis-related phenotypes ( 20548944) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Survival in colorectal cancer ( 26586795) Temperament (bipolar disorder) ( 22365631)
Interacting Genes		3 interacting genes: CREB3L4 NTNG1 WHRN	6 interacting genes: CASK LRP4 LRRC4C MYO15A MYO7A RPS6KA1
Entrez ID		57689	25861
HPRD ID		12303	09718
Ensembl ID		ENSG00000148948	ENSG00000095397
Uniprot IDs		Q4JIV9 Q4JIW0 Q9HCJ2	B9EGE6 Q9P202
PDB IDs		3ZYJ	1UEZ 1UF1 1UFX
Enriched GO Terms of Interacting Partners?
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