WHRN and MYO7A

Number of citations of the paper that reports this interaction (PubMedID 15590698)
79

Data Source:
HPRD (in vitro)

		WHRN	MYO7A
Description		whirlin	myosin VIIA
Image
GO Annotations	Cellular Component	Photoreceptor Inner Segment Stereocilia Ankle Link Stereocilia Ankle Link Complex Cytoplasm Actin Filament Plasma Membrane Cell Junction Growth Cone Photoreceptor Connecting Cilium Stereocilium Stereocilium Tip Ciliary Basal Body Neuronal Cell Body Synapse Periciliary Membrane Compartment USH2 Complex	Photoreceptor Outer Segment Photoreceptor Inner Segment Cell Cytoplasm Lysosomal Membrane Cytosol Microvillus Cell Cortex Actin Cytoskeleton Apical Plasma Membrane Cell Junction Myosin VII Complex Vesicle Photoreceptor Connecting Cilium Stereocilium Melanosome Synapse Stereocilium Base Upper Tip-link Density
	Molecular Function	Protein Binding Identical Protein Binding	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Protein Domain Specific Binding Spectrin Binding Actin-dependent ATPase Activity Identical Protein Binding ADP Binding Protein N-terminus Binding Actin Filament Binding
	Biological Process	Retina Homeostasis Sensory Perception Of Sound Positive Regulation Of Gene Expression Cerebellar Purkinje Cell Layer Formation Establishment Of Protein Localization Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Sensory Perception Of Light Stimulus Auditory Receptor Cell Stereocilium Organization Inner Ear Receptor Cell Development Inner Ear Receptor Cell Stereocilium Organization Paranodal Junction Maintenance	Phagolysosome Assembly Intracellular Protein Transport Actin Filament Organization Lysosome Organization Sensory Organ Development Visual Perception Sensory Perception Of Sound Actin Filament-based Movement Vesicle Transport Along Actin Filament Cellular Protein Localization Eye Photoreceptor Cell Development Mechanoreceptor Differentiation Post-embryonic Animal Organ Morphogenesis Sensory Perception Of Light Stimulus Equilibrioception Pigment Granule Transport Auditory Receptor Cell Stereocilium Organization
Pathways			The canonical retinoid cycle in rods (twilight vision)
Drugs
Diseases		Usher syndrome (US) Deafness, autosomal recessive	Usher syndrome (US) Deafness, autosomal dominant Deafness, autosomal recessive
GWAS			Lewy body disease ( 25188341) Post bronchodilator FEV1/FVC ratio ( 26634245) Tourette syndrome ( 30818990)
Interacting Genes		6 interacting genes: CASK LRP4 LRRC4C MYO15A MYO7A RPS6KA1	12 interacting genes: ACTA1 CALM1 CDH23 KEAP1 KHDRBS1 LINC00839 MAP2 MYRIP PRKAR1A USH1C VEZT WHRN
Entrez ID		25861	4647
HPRD ID		09718	02043
Ensembl ID		ENSG00000095397	ENSG00000137474
Uniprot IDs		B9EGE6 Q9P202	Q13402
PDB IDs		1UEZ 1UF1 1UFX	5MV9
Enriched GO Terms of Interacting Partners?
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