PTK7 and PPM1F

Number of citations of the paper that reports this interaction (PubMedID 28065597)
26

Data Source:
BioGRID (two hybrid)

		PTK7	PPM1F
Description		protein tyrosine kinase 7 (inactive)	protein phosphatase, Mg2+/Mn2+ dependent 1F
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion	Nucleus Cytosol Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway	Protein Serine/threonine Phosphatase Activity Magnesium-dependent Protein Serine/threonine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Calmodulin-dependent Protein Phosphatase Activity Metal Ion Binding
	Biological Process	Establishment Of Planar Polarity Ventricular Septum Development Axis Elongation Protein Phosphorylation Cell Adhesion Signal Transduction Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Reorganization Wound Healing Establishment Of Epithelial Cell Apical/basal Polarity Convergent Extension Lung-associated Mesenchyme Development Coronary Vasculature Development Cellular Response To Retinoic Acid Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Canonical Wnt Signaling Pathway	Negative Regulation Of Protein Kinase Activity Positive Regulation Of Gene Expression Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cell-substrate Adhesion Histone Dephosphorylation Positive Regulation Of Cell Migration Negative Regulation Of Peptidyl-serine Phosphorylation Cellular Response To Drug Peptidyl-threonine Dephosphorylation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Growth Positive Regulation Of Chemotaxis Negative Regulation Of Protein Transport Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Peptidyl-serine Dephosphorylation Intrinsic Apoptotic Signaling Pathway Regulation Of Cellular Protein Localization Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin
Pathways			Negative regulation of NMDA receptor-mediated neuronal transmission
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Adventurousness ( 30643258) Attention deficit hyperactivity disorder ( 18839057) Bipolar disorder ( 31043756)
Interacting Genes		32 interacting genes: CDC14A CLNK CTDSP2 DUPD1 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 ERBB2 ILKAP MTMR1 MTMR10 MTMR6 MTMR9 PPM1A PPM1B PPM1F PPM1K PPP3CA PPP3CB PTEN PTPN11 PTPN12 PTPN6 PTPN7 PTPRR STYX TPTE TPTE2	17 interacting genes: AATK ARHGEF7 CAMK2A ERBB2 ERBB3 ERBB4 FAM161A FEM1A FEM1B LATS1 LMTK2 MARS1 PAK1 PRKAA1 PTK7 ROR1 ROR2
Entrez ID		5754	9647
HPRD ID		03534	10163
Ensembl ID		ENSG00000112655	ENSG00000100034
Uniprot IDs		Q13308	B5MCT7 P49593
PDB IDs
Enriched GO Terms of Interacting Partners?
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