PPM1F and FAM161A

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)

		PPM1F	FAM161A
Description		protein phosphatase, Mg2+/Mn2+ dependent 1F	FAM161 centrosomal protein A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Protein-containing Complex Perinuclear Region Of Cytoplasm	Astral Microtubule Photoreceptor Inner Segment Centrosome Spindle Microtubule Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Mitotic Spindle Mitotic Spindle Pole
	Molecular Function	Protein Serine/threonine Phosphatase Activity Magnesium-dependent Protein Serine/threonine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Calmodulin-dependent Protein Phosphatase Activity Metal Ion Binding	Protein Binding Microtubule Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Positive Regulation Of Gene Expression Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cell-substrate Adhesion Histone Dephosphorylation Positive Regulation Of Cell Migration Negative Regulation Of Peptidyl-serine Phosphorylation Cellular Response To Drug Peptidyl-threonine Dephosphorylation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Growth Positive Regulation Of Chemotaxis Negative Regulation Of Protein Transport Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Peptidyl-serine Dephosphorylation Intrinsic Apoptotic Signaling Pathway Regulation Of Cellular Protein Localization Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin	Visual Perception Cilium Organization Response To Stimulus Cilium Assembly Positive Regulation Of Protein Acetylation
Pathways		Negative regulation of NMDA receptor-mediated neuronal transmission
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS		Adventurousness ( 30643258) Attention deficit hyperactivity disorder ( 18839057) Bipolar disorder ( 31043756)	Atrial fibrillation ( 29892015) Erectile dysfunction ( 30583798) Systemic lupus erythematosus ( 28714469)
Interacting Genes		17 interacting genes: AATK ARHGEF7 CAMK2A ERBB2 ERBB3 ERBB4 FAM161A FEM1A FEM1B LATS1 LMTK2 MARS1 PAK1 PRKAA1 PTK7 ROR1 ROR2	66 interacting genes: BEND3 BEND5 BRCA1 CADPS CALCOCO1 CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC33 CCDC57 CCNDBP1 CDR2 CEP44 CEP57L1 CEP63 CEP70 DHX32 DOCK8 DVL2 EHMT2 FAM9B FSD2 GOLGA2 HMBOX1 IKZF1 KASH5 KIAA0753 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 LMNA LZTS2 MCM6 MDFI MID2 MIPOL1 MTUS2 NECAB2 NINL NUTM1 PDE4DIP PHC2 PNMA2 PPFIA1 PPM1F RINT1 RUNDC3A SSX2IP STX11 SYCE1 TFIP11 TMCC2 TNIP1 TRAF1 TRIM15 TRIM37 TRIM54 TSGA10 TXLNB ZBTB1 ZBTB14 ZBTB43 ZBTB8A
Entrez ID		9647	84140
HPRD ID		10163	18996
Ensembl ID		ENSG00000100034	ENSG00000170264
Uniprot IDs		B5MCT7 P49593	Q3B820
PDB IDs
Enriched GO Terms of Interacting Partners?
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