PAK5 and GCC1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PAK5	GCC1
Description		p21 (RAC1) activated kinase 5	GRIP and coiled-coil domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Synapse	Golgi Membrane Golgi Apparatus Cytosol
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Protein Binding
	Biological Process	Regulation Of Cell Growth Apoptotic Process Cytoskeleton Organization Signal Transduction Regulation Of Mitotic Cell Cycle Learning Memory Locomotory Behavior Cell Proliferation Cell Migration Signal Transduction By Protein Phosphorylation Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Activation of RAC1	Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Atopy ( 28927820) Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701)	Feeling worry ( 29500382) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Medication adherence in chronic diseases ( 25317111) Type 2 diabetes ( 26818947 22158537 30718926)
Interacting Genes		21 interacting genes: ARMC7 ATPAF2 BAD CARD9 CCNG1 CDC42 CRBN EMD EXOSC1 FHL3 GCC1 INKA1 LENG1 LZTS2 PDLIM7 PRPF31 PSMF1 RAC1 SORBS3 TUBGCP4 UXT	44 interacting genes: ABI2 ADGRE5 AMOTL2 APP ARL1 ATF4 ATN1 BIRC2 BRCA1 C1orf94 CCDC85B CEP57 CEP70 COIL CPSF7 CRHR2 DNAJA3 FAM71F2 FBF1 GLI1 GOLGA2 GTF2I HILPDA IKBKG ITSN1 KHSRP KIAA0753 KIAA1217 LZTS2 MCRS1 NAB2 NAV1 NECAB2 NINL OIP5 PAK5 PCDHA1 RBM28 SMARCD1 SPOP TFIP11 TRIM29 USHBP1 ZNF276
Entrez ID		57144	79571
HPRD ID		06423	07599
Ensembl ID		ENSG00000101349	ENSG00000179562
Uniprot IDs		B0AZM9 Q9P286	A4D0Z4 Q96CN9
PDB IDs		2F57
Enriched GO Terms of Interacting Partners?
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